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Primary Antibodies
QPRT Antibody
Background
This protein is a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease.
Additional Names
Quinolinate phosphoribosyltransferase, Nicotinate-nucleotide pyrophosphorylase (Carboxylating)
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Description
Left: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
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Location
The gene that codes for this protein is at chromosomal location 16p11.2.
Purification
Immunoaffinity Purified
Clonality / Clone
This is a polyclonal antibody.
Host
QPRT antibody was raised in chicken.
Please use anti-chicken secondary antibodies.
Immunogen
123-237
Application
Quinolinate phosphoribosyltransferase antibody can be used for the detection of Quinolinate phosphoribosyltransferase by Western Blot.
Tested Application
WB
Buffer
Phosphate-Buffered Saline. No preservatives added.
Storage
QPRT antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Species Reactivity
H
Protein GI Number
45269149
Protein Accession Number
NP_055113.2
Molecular Weight
30.8 kDa (calculated)
Short Description
Nicotinate-nucleotide pyrophosphorylase (Carboxylating)
This product belongs to the following categories:
Related Products
Datasheet 0801-W
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