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Primary Antibodies
PTPN21 Antibody
Background
PTPN21; protein tyrosine phosphatase, non-receptor type 21; protein tyrosine phosphatase D1. PTPN21 is a member of the protein tyrosine phosphatase (PTP) family. PTPN21 contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. It interacts with BMX/ETK, and this interaction increases the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis.
Additional Names
PTPN21
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Description
PTPN21 IgY Antibody
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Location
The gene that codes for this protein is at chromosomal location 14q31.3.
Purification
Antigen affinity-purified
Clonality / Clone
This is a polyclonal antibody.
Host
PTPN21 antibody was raised in chicken.
Please use anti-chicken secondary antibodies.
Immunogen
580-837
Application
PTPN21 antibody can be used for the detection of PTPN21 by Western blot, may also work for IHC and ICC.
Tested Application
WB
Buffer
Phosphate-Buffered Saline. No preservatives added.
Storage
PTPN21 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Species Reactivity
H
Protein GI Number
5902032
Protein Accession Number
NP_008970.1
Molecular Weight
133.3 kDa (calculated)
Short Description
Protein tyrosine phosphatase, non-receptor type 21
This product belongs to the following categories:
References- Moller, N. P. H., Moller, K. B., Lammers, R., Kharitonenkov, A., Sures, I., Ullrich, A. Src kinase associates with a member of a distinct subfamily of protein-tyrosine phosphatases containing an ezrin-like domain. Proc. Nat. Acad. Sci. 91: 7477-7481, 1994.
Datasheet 0801-W
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