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Primary Antibodies
OAS1 Antibody
Background
2',5'-oligoadenylate synthetase 1 isoform E16; 2',5'-oligoadenylate synthetase; 2',5'-oligoadenylate synthetase 1 (40-46 kD). This protein is an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance.
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Description
OAS1 IgY Antibody
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Location
The gene that codes for this protein is at chromosomal location 12q24.1.
Purification
Antigen affinity-purified
Clonality / Clone
This is a polyclonal antibody.
Host
OAS1 antibody was raised in chicken.
Please use anti-chicken secondary antibodies.
Immunogen
1-364
Application
OAS1 antibody can be used for the detection of OAS1 by Western blot, may also work for IHC and ICC.
Tested Application
WB
Buffer
Phosphate-Buffered Saline. No preservatives added.
Storage
OAS1 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Species Reactivity
H, M, R
Protein GI Number
8051623
Protein Accession Number
NP_002525.1
Molecular Weight
46.1 kDa (calculated)
Short Description
Oligoadenylate synthetase 1 isoform E16
This product belongs to the following categories:
References- Behera, A. K., Kumar,M., Lockey, R. F. and Mohapatra, S. S. 2'-5' Oligoadenylate synthetase plays a critical role in interferon-gamma inhibition of respiratory syncytial virus infection of human epithelial cells. J. Biol. Chem. 277 (28), 25601-25608 (2002).
Datasheet 0801-W
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