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Primary Antibodies
NUP62 Antibody
Background
FUNCTION: Essential component of the nuclear pore complex. The N-terminal is probably involved in nucleocytoplasmic transport. The C-terminal is probably involved in protein-protein interaction via coiled-coil formation and may function in anchorage of p62 to the pore complex.
SUBUNIT: Component of the p62 complex, a complex at least composed of NUP62, NUP54, and NUPL1 (By similarity)
SUBCELLULAR LOCATION: Nucleus; nuclear envelope; nuclear pore complex. Central region of the nuclear pore, within the transporter. During mitotic cell division, it associates with the poles of the mitotic spindle.
DOMAIN: Contains F-X-F-G repeats.
SIMILARITY: Belongs to the NUP62 family.
SUMMARY: Nuclear pore complexes mediate active transport of protein and RNA through the nuclear envelope. Nucleoporins are glycoproteins that contain N-acetylglucosamine residues O-linked to serine and possibly threonine. They are localized to the central 'transporter' region of the pore complex.
Additional Names
Nuclear pore glycoprotein p62, 62 kDa nucleoporin
Location
The gene that codes for this protein is at chromosomal location 19q13.33.
Purification
Immunoaffinity Purified
Clonality / Clone
This is a polyclonal antibody.
Host
NUP62 antibody was raised in chicken.
Please use anti-chicken secondary antibodies.
Immunogen
328-522
Application
Nuclear pore glycoprotein p62 antibody can be used for the detection of Nuclear pore glycoprotein p62 by Western Blot.
Tested Application
WB
Buffer
Phosphate-Buffered Saline. No preservatives added.
Storage
NUP62 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Species Reactivity
H
Protein GI Number
7705355
Protein Accession Number
NP_057637.1
Molecular Weight
53.3 kDa (calculated)
Short Description
Nuclear pore glycoprotein p62, 62 kDa nucleoporin
This product belongs to the following categories:
Datasheet 0801-W
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