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Primary Antibodies
MTHFD2 Antibody
Background
CATALYTIC ACTIVITY: 5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate.
SUBUNIT: Homodimer.
SIMILARITY: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
COFACTOR: Magnesium.
SUBCELLULAR LOCATION: Mitochondrion.
DEVELOPMENTAL STAGE: Expressed only in developing normal tissues.
MISCELLANEOUS: This NAD-dependent bifunctional enzyme has very different kinetic properties than the larger NADP-dependent trifunctional enzyme and is unique in that it requires formation of an enzyme-magnesium complex to allow binding of NAD.
Additional Names
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial
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Description
Left: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
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Location
The gene that codes for this protein is at chromosomal location 2p13.1.
Purification
Immunoaffinity Purified
Clonality / Clone
This is a polyclonal antibody.
Host
MTHFD2 antibody was raised in chicken.
Please use anti-chicken secondary antibodies.
Immunogen
28-213
Application
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial antibody can be used for the detection of Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial by Western Blot.
Tested Application
WB
Buffer
Phosphate-Buffered Saline. No preservatives added.
Storage
MTHFD2 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Species Reactivity
H, M
Protein GI Number
5729935
Protein Accession Number
NP_006627.1
Molecular Weight
37.3 kDa (calculated)
Short Description
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial,
This product belongs to the following categories:
Related Products
Datasheet 0801-W
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