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Primary Antibodies
MMP2 Antibody
Background
Matrix metalloproteinase 2 preprotein; gelatinase A; 72 kD type IV collagenase; gelatinase neutrophil. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes as well as in disease processes. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP2 degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response.
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Description
MMP2 IgY Antibody
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Location
The gene that codes for this protein is at chromosomal location 16q13-q21.
Purification
Antigen affinity-purified
Clonality / Clone
This is a polyclonal antibody.
Host
MMP2 antibody was raised in chicken.
Please use anti-chicken secondary antibodies.
Immunogen
60-180
Application
MMP2 antibody can be used for the detection of MMP2 by Western blot, may also work for IHC and ICC.
Tested Application
WB
Buffer
Phosphate-Buffered Saline. No preservatives added.
Storage
MMP2 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Species Reactivity
H, M, R
Protein GI Number
11342666
Protein Accession Number
NP_004521.1
Molecular Weight
73.9 kDa (calculated)
Short Description
Matrix metalloproteinase 2 preproprotein; gelatinase A
This product belongs to the following categories:
References- Morgunova, E., Tuuttila, A., Bergmann, U., Isupov, M., Lindqvist, Y., Schneider, G., Tryggvason, K. Structure of human pro-matrix metalloproteinase-2: activation mechanism revealed. Science 284: 1667-1670, 1999.
Datasheet 0801-W
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