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Primary Antibodies
MAP3K7IP2 Antibody
Background
MAP3K7IP2 is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of NF.:B and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serving as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF.:B (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.
Additional Names
MAP3K7IP2
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Description
Left: Western blot analysis of MAP3K7IP2 in HepG2 Cell Lysate using MAP3K7IP2 antibody at 5 μg/ml (12% gel).
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Purification
Antibody is purified by peptide affinity chromatography method.
Clonality / Clone
This is a polyclonal antibody.
Host
MAP3K7IP2 antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAP3K7IP2.
Application
MAP3K7IP2 antibody can be used for detection of MAP3K7IP2 by ELISA at 1:312500. MAP3K7IP2 antibody can be used for detection of MAP3K7IP2 by western blot at 2.0/ml.
Tested Application
E, WB, IHC
Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μl of distilled water. Final antibody concentration is 1 mg/ml.
Storage
For longer periods of storage, store MAP3K7IP2 antibody at -20˚C. Avoid repeat freeze-thaw cycles.
Species Reactivity
H, M, R, D
Protein Accession Number
NP_055908
Molecular Weight
76 kDa
Short Description
MAP3K7IP2 (mitogen-activated protein kinase kinase kinase 7 interacting protein 2)
This product belongs to the following categories:
References- Kanayama, A., et al., ,(2004) Mol. Cell 15 (4), 535-548.
Datasheet 10-01W
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