|
Primary Antibodies
M6PR Antibody
Background
Chicken polyclonal IgY Antibodies against cation-dependent mannose-6-phosphate receptor. This protein is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein that localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.
|
Description
M6PR IgY Antibody
|
Location
The gene that codes for this protein is at chromosomal location 12p13.
Purification
Antigen affinity-purified
Clonality / Clone
This is a polyclonal antibody.
Host
M6PR antibody was raised in chicken.
Please use anti-chicken secondary antibodies.
Immunogen
60-114
Application
M6PR antibody can be used for the detection of M6PR by ICC, may also work for IHC.
Tested Application
ICC
Buffer
Phosphate-Buffered Saline. No preservatives added.
Storage
M6PR antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Species Reactivity
H, M, R
Protein GI Number
4505061
Protein Accession Number
NP_002346.1
Molecular Weight
31 kDa (calculated)
This product belongs to the following categories:
References- Klumperman,J. et al. Differences in the endosomal distributions of the two mannose 6-phosphate receptors J. Cell Biol. 121 (5), 997-1010 (1993)
Datasheet 0801-W
|
|
