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Primary Antibodies
LMNA Antibody
Background
Lamin A protein. Lamins A and C are two proteins of the nuclear lamina. They form dimers through their rod domain and interact with chromatin and integral proteins of the inner nuclear membrane through binding sites located in their carboxy-terminal globular tail.
Additional Names
LaminA
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Description
LaminA IgY Antibody
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Location
The gene that codes for this protein is at chromosomal location 1q21.2-q21.3.
Purification
Antigen affinity-purified
Clonality / Clone
This is a polyclonal antibody.
Host
LMNA antibody was raised in chicken.
Please use anti-chicken secondary antibodies.
Immunogen
64-122
Application
LaminA antibody can be used for the detection of LaminA by Western blot, may also work for IHC and ICC.
Tested Application
WB
Buffer
Phosphate-Buffered Saline. No preservatives added.
Storage
LMNA antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Species Reactivity
H, M, R
Protein GI Number
386856
Protein Accession Number
AAA36160.1
Molecular Weight
74.1 kDa (calculated)
Short Description
Lamin A protein
This product belongs to the following categories:
References- Fatkin, D., MacRae, C., Sasaki, T., Wolff, M. R., Porcu, M., Frenneaux, M., Atherton, J., Vidaillet, H. J., Jr., Spudich, S., De Girolami, U., Seidman, J. G., Seidman, C. E. Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease. New Eng. J. Med. 341: 1715-1724, 1999.
Datasheet 0801-W
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