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Primary Antibodies
LIAR Antibody
Background
Ankyrin (ANK) repeats mediate protein-protein interactions in diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20. ANK repeats may occur in combinations with other types of domains. The structural repeat unit contains two anti-parallel helices and a beta-hairpin, with repeats stacked in a superhelical arrangement. LIAR, also known as ANKRD54, is a recently identified ANK repeat-containing protein that is predominantly expressed in tissues rich in cilliated cells, such as olfactory sensory neurons and is predicted to be important to cilia. At least three isoforms of LIAR are known to exist.
Additional Names
LIAR, Lyn-interacting ankyrin repeat protein, ankyrin repeat domain 54, ANKRD54
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Description
Left: Western blot analysis of LIAR in mouse kidney tissue lysate with LIAR antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.
Below: Immunohistochemistry of LIAR in mouse kidney tissue with LIAR antibody at 2.5 μg/ml.
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Other Product Images
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Source
LIAR antibody was raised against a 16 amino acid peptide near the carboxy terminus of human LIAR.
Purification
Affinity chromatography purified via peptide column
Clonality / Clone
This is a polyclonal antibody.
Host
LIAR antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
Application
LIAR antibody can be used for detection of LIAR by Western blot at 1 - 2 μg/ml.
Tested Application
E, WB, IHC
Buffer
Antibody is supplied in PBS containing 0.02% sodium azide.
Blocking Peptide
Cat.No. 5261P - LIAR Peptide
Storage
LIAR antibody can be stored at 4˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Positive Control
- Cat. No. 1405 - Mouse Kidney Tissue Lysate
Species Reactivity
H, M, R
Protein GI Number
20270347
Protein Accession Number
NP_620152
Short Description
Ankyrin repeat domain 54
This product belongs to the following categories:
References- Li J, Mahajan A, and Tsai MD. Ankyrin repeat: a unique motif mediating protein-protein interactions. Biochemistry 2006; 45:15168-78.
Datasheet 09-01W
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