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Catalog Number:

3629P


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REDI-Ladder™ Molecular Weight Marker


Antibody Production


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Peptides

LAMP-1 Peptide

Background

LAMP-1 Peptide

Location

15 amino acids near the center of human LAMP-1.

Application

LAMP-1 peptide is used for blocking the activity of LAMP-1 antibody (Cat. No. 3629). It usually blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37˚C. For research use only.

Tested Application

Bl

Buffer

PBS containing 0.02% sodium azide

Storage

LAMP-1 peptide is supplied as 200 μg/ml, 50 μg/vial, in PBS pH7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide. Store at -20˚C, stable for one year.

Species Reactivity

n/a

Species

H

Short Description

LAMP-1 peptide

This product belongs to the following categories:

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References

  1. Chen JW, Murphy TL, Willingham MC, et al. Identification of two lysosomal membrane glycoproteins. J. Cell Biol. 1985; 101:85-95.
  2. Kisen GO, Tessitore L, Costelli P, et al. Reduced autophagic activity in primary rat hepatocellular carcinoma and ascites hepatoma cells. Carcinogenesis 1993; 14:2501-5.
  3. Kamada Y, Funakoshi T, Shintani T, et al. Tor-mediated induction of autophagy via Apg1 protein kinase complex. J. Cell. Biol. 2000; 150:1507-13.
  4. Granger BL, Green SA, Gabel CA, et al. Characterization and cloning of the lgp110, a lysosomal glycoprotein from mouse and rat cells. J. Biol. Chem. 1990; 265:12036-43. 5. Tanaka Y, Guhde G, Suter A, et al. Accumulation of autophagic vacuoles and cardiopathy in LAMP-2-deficient mice. Nature 2000; 902-6. 6. Nishino I, Fu J, Tanji K, et al. Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease). Nature 2000; 906-10. 7. Gough NR, Hatem CL, and Fambrough DM. The family of LAMP-2 proteins arises by alternative splicing from a single gene: characterization of the avian LAMP-2 gene and identification of mammalian homologs of LAMP-2b and LAMP-2c. DNA Cell Biol. 1995; 14:863-7.


Datasheet 0801-W

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