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Primary Antibodies
KAT Antibody
Background
FUNCTION: Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. This activity may promote rapid reorganization of cellular microtubule arrays, such as during disassembly of interphase microtubules at the G2-M transition. May also be required for microtubule release from the centrosome after nucleation. In mitotic spindles this could allow depolymerization of the microtubule end proximal to the centrosome, and subsequent poleward microtubule flux. In neurons, microtubule release within the cell body may allow their subsequent transport into neuronal processes by microtubule dependent motor proteins. This transport is required for axonal growth (By similarity).
Additional Names
Katanin p80 WD40containing subunit B1, Katanin p80 subunit B1, p80 katanin
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Description
Left: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
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Location
The gene that codes for this protein is at chromosomal location 16q13.
Purification
Immunoaffinity Purified
Clonality / Clone
This is a polyclonal antibody.
Host
KAT antibody was raised in chicken.
Please use anti-chicken secondary antibodies.
Immunogen
301-511
Application
Katanin p80 WD40-containing subunit B1 antibody can be used for the detection of Katanin p80 WD40-containing subunit B1 by Western Blot.
Tested Application
WB
Buffer
Phosphate-Buffered Saline. No preservatives added.
Storage
KAT antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Species Reactivity
H, M, R
Protein GI Number
5031817
Protein Accession Number
NP_005877.1
Molecular Weight
72.3 kDa (calculated)
Short Description
Katanin p80 WD40-containing subunit B1
This product belongs to the following categories:
Related Products
Datasheet 0801-W
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