|
Primary Antibodies
KALRN Antibody
Background
KALRN Antibody. This antibody is expected to recognize reported isoforms NP_001019831.2 and NP_003938.1.
Additional Names
KALRN, kalirin, RhoGEF kinase, DUET, FLJ16443, HAPIP, TRAD, duo, huntingtin-associated protein interacting protein (duo), serine/threonine kinase with Dbl- and pleckstrin homology domains
Source
KALRN antibody was raised against a synthetic peptide of KALRN.
Purification
KALRN antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Clonality / Clone
This is a polyclonal antibody.
Host
KALRN antibody was raised in goat.
Please use anti-goat secondary antibodies.
Application
Peptide ELISA: antibody detection limit dilution 1:64000. Preliminary experiments gave an approx 49kDa band in Human, Mouse and Rat Brain lysates after 0.3μg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 340kDa according to NP_001019831.2 and of 192kDa according to NP_003938.1. The 49kDa band was successfully blocked by incubation with the immunizing peptide.
Tested Application
E
Buffer
KALRN antibody is supplied as 0.1mg of purified antibody, 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Blocking Peptide
Cat. No. 46-975P - KALRN Peptide
Storage
Aliquot and store at -20°C. Minimize freezing and thawing.
Species Reactivity
H, M, R, B, Hr
Protein Accession Number
NP_001019831.2, NP_003938.1, NP_008995.2
Short Description
(NT) KALRN
This product belongs to the following categories:
References- Xie Z, Srivastava DP, Photowala H, Kai L, Cahill ME, Woolfrey KM, Shum CY, Surmeier DJ, Penzes P. Kalirin-7 controls activity-dependent structural and functional plasticity of dendritic spines. Neuron. 2007 Nov 21;56(4):640-56.
Datasheet 09-01W
|
|
