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Peptides
IRE1p Peptide
Background
IRE1p (N-Terminus) Peptide
Location
15 amino acids near the amino terminus of human IRE1p.
Application
IRE1p peptide is used for blocking the activity of IRE1p antibody (Cat. No. 3657). It usually blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37˚C. For research use only.
Tested Application
Bl
Buffer
PBS containing 0.02% sodium azide
Storage
IRE1p peptide is supplied as 200 μg/ml, 50 μg/vial, in PBS pH7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide. Store at -20˚C, stable for one year.
Species Reactivity
n/a
Species
H
Short Description
(NT) IRE1p peptide
This product belongs to the following categories:
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References- Miyoshi K, Katayama T, Imaizumi K, et al. Characterization of mouse Ire1 alpha: cloning, mRNA localization in the brain and functional analysis in a neural cell line. Brain Res. Mol. Brain Res. 2000; 85:68-76.
- Janeway CA Jr. and Medzhitov R. Innate immune recognition. Annu. Rev. Immunol. 2002; 20:197-216.
- McGettrick AF and O’Neill LAJ. The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction. Mol Imm. 2004; 41:577-82.
- Alexopoulou L, Holt AC, Medzhitov R, et al. Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3. Nature 2001; 413:732-8. 5. Guillot L, Le Goffic R, Bloch S, et al. Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus. J. Biol. Chem. 2005; 280:5571-80. 6. Wang T, Town T, Alexopoulou L, et al. Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis. Nat. Med. 2004; 10:1366-73.
Datasheet 0801-W
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