|
Primary Antibodies
GABRP Antibody
Background
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. The subunit encoded GABRP is expressed in several non-neuronal tissues including the uterus and ovaries. This subunit can assemble with known GABA A receptor subunits, and the presence of this subunit alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone.The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. The subunit encoded by this gene is expressed in several non-neuronal tissues including the uterus and ovaries. This subunit can assemble with known GABA A receptor subunits, and the presence of this subunit alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone.
Additional Names
GABRP, MGC126386, MGC126387
|
Description
Left: Western blot analysis of GABRP in HepG2 Cell Lysate using GABRP antibody at 0.25 μg/ml (12% gel).
|
Purification
Antibody is purified by peptide affinity chromatography method.
Clonality / Clone
This is a polyclonal antibody.
Host
GABRP antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GABRP.
Application
GABRP antibody can be used for detection of GABRP by ELISA at 1:1562500. GABRP antibody can be used for detection of GABRP by western blot at 0.25 μg/ml, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Tested Application
E, WB
Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μl of distilled water. Final antibody concentration is 1 mg/ml.
Storage
For longer periods of storage, store GABRP antibody at -20˚C. Avoid repeat freeze-thaw cycles.
Species Reactivity
H, M, R, D
Protein Accession Number
NP_055026
Molecular Weight
51kDa
Short Description
GABRP (gamma-aminobutyric acid (GABA) A receptor, pi)
This product belongs to the following categories:
References- Neelands,T.R. (1999) Mol. Pharmacol. 56 (3), 598-610.
Datasheet 10-01W
|
|
