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Primary Antibodies
GABRD Antibody
Background
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. The GABRD gene encodes the delta subunit.Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit.
Additional Names
GABRD, MGC45284
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Description
Left: Western blot analysis of GABRD in Jurkat Cell Lysate using GABRD antibody at 1 μg/ml (12% gel).
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Purification
Antibody is purified by peptide affinity chromatography method.
Clonality / Clone
This is a polyclonal antibody.
Host
GABRD antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GABRD.
Application
GABRD antibody can be used for detection of GABRD by ELISA at 1:62500. GABRD antibody can be used for detection of GABRD by western blot at 1.0 μg/ml, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Tested Application
E, WB
Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μl of distilled water. Final antibody concentration is 1 mg/ml.
Storage
For longer periods of storage, store GABRD antibody at -20˚C. Avoid repeat freeze-thaw cycles.
Species Reactivity
H, M, R, D
Protein Accession Number
NP_000806
Molecular Weight
51kDa
Short Description
GABRD (gamma-aminobutyric acid (GABA) A receptor, delta)
This product belongs to the following categories:
References- Windpassinger,C., Gene 292 (1-2), 25-31 (2002).
Datasheet 10-01W
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