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Primary Antibodies
GABPA Antibody
Background
GA Binding Protein . chain (GABP-. subunit, GABPA, nuclear respiratory factor-2 subunit . transcription factor E4TF1-60) is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype.
Additional Names
GABPA
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Description
Left: Western blot analysis of GABPA in Jurkat Cell Lysate using GABPA antibody at 2 μg/ml (12% gel).
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Purification
Antibody is supplied as total IgG.
Clonality / Clone
This is a polyclonal antibody.
Host
GABPA antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GABPA.
Application
GABPA antibody can be used for detection of GABPA by ELISA at 1:312500. GABPA antibody can be used for detection of GABPA by western blot at 0.5-1.0 μg/ml, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Tested Application
E, WB, IHC
Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 200 μl of distilled water. Final antibody concentration is 1 mg/ml.
Storage
For longer periods of storage, store GABPA antibody at -20˚C. Avoid repeat freeze-thaw cycles.
Species Reactivity
H, M, R, D, ZF
Protein Accession Number
NP_002031
Molecular Weight
51kDa, 97kDa
Short Description
GABPA (GA binding protein transcription factor, alpha subunit 60kDa)
This product belongs to the following categories:
References- Xue, H.H., et al., (2004) Nat.Immunol.5(10),1036-1044.
Datasheet 10-01W
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