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Primary Antibodies
GABPA Antibody
Background
GA Binding Protein α chain (GABP-α subunit, GABPA, nuclear respiratory factor-2 subunit α transcription factor E4TF1-60) is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype.
Additional Names
E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A
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Description
Left: Western blot analysis of GABPA in Jurkat cell lysates using anti-GABPA.
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Purification
Rabbit total IgG
Clonality / Clone
This is a polyclonal antibody.
Host
GABPA antibody was raised in rabbit.
Please use anti-rabbit IgG secondary antibodies.
Immunogen
GABPA antibody was produced in rabbits immunized with a synthetic peptide corresponding to a region of human GABPA.
Application
GABPA antibody can be used for Western blot at a suggested dilution of 0.5-1.0 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti Rabbit IgG should be diluted in 1: 50,000 - 100,003 as secondary antibody. The protein size is 454 , 878 amino acids.
Tested Application
WB, IHC
Buffer
Antibody is supplied in PBS buffer with 2% sucrose. Product may ship lyophilized. To reconstitute add 100μl of distilled water making the final concentration 1 mg/ml.
Storage
GABPA antibody is supplied in PBS buffer containing 0.02% sodium azide. For longer periods of storage, store at -20ºC. Avoid repeat freeze-thaw cycle.
Positive Control
- Cat. No. 1205 - Jurkat Cell Lysate
Species Reactivity
H
Protein Accession Number
NP_002031
Molecular Weight
51kDa
Short Description
Anti-GA Binding Protein α chain (GABPA)
This product belongs to the following categories:
Related Products
References- Xue, H.H., et al., (2004) Nat.Immunol.5(10),1036-1044
Datasheet 0802-W
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