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Primary Antibodies
DRD1 Antibody
Background
DRD1, a Dopamine Receptor, mediates the effect of the neurotransmitter dopamine, an intermediate in the biosynthesis of noradrenaline and adrenaline. It is involved in the control of motor activity and cognitive memory. Downregulation of DRD1 leads to severe impairments in working memory and to locomotor hyperactivity, which are observed in diseases such as schizophrenia, Parkinson's disease, affective disorders, and attention deficit hyperactivity disorder. DRD1 enhances smooth muscle contraction and vasodilation in the heart. It also modulates sodium transport in the kidney and is involved in the pathogenesis of hypertension.
Additional Names
DRD1, D, DADR, DRD1A, d-1 dopamine receptor, d1 dopamine receptor, d1a dopamine receptor, d1a receptor, dopamine 1 receptor, dopamine d-1 receptor, dopamine d1 receptor, dopamine d1a receptor, dopamine receptor d1, dopamine receptor d1a, dopamine type 1 receptor, drd1, drd1a
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Description
Left: Immunohistochemistry staining of DRD1 in brain (formalin-fixed paraffin-embedded) using DRD1 antibody.
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Purification
Immunoaffinity Chromatography
Clonality / Clone
This is a polyclonal antibody.
Host
DRD1 antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
Immunogen
DRD1 antibody was raised against the C-terminal cytoplasmic domain of DRD1. (Human)
Application
DRD1 antibody can be used for detection of DRD1 by ELISA, IHC-parafin (1 - 5 μg/ml).
Tested Application
E, IHC
Buffer
DRD1 antibody is supplied in PBS, 0.1% sodium azide.
Storage
DRD1 antibody can be stored at -70˚C for long term storage, and 4˚C for short term storage.
Species Reactivity
H
Formulation
Weight: 50 μg
Volume: 50 μl
Concentration: 1 mg/ml
Short Description
Dopamine Receptor D1
This product belongs to the following categories:
Datasheet 09-01W
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