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Catalog Number:

1158P


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REDI-Ladder™ Molecular Weight Marker


Antibody Production


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Peptides

DR3 Peptide

Background

DR3 (Extracellular Domain) Peptide

Location

19 amino acids near the extracellular domain of human DR3.

Application

DR3 peptide is used for blocking the activity of Anti-DR3 (Cat. No. 1158). Incubating the peptide with equal volume of antibody for 30 min at 37˚C usually completely blocks the antibody activity in Western blotting.

Tested Application

Bl

Buffer

PBS containing 0.02% sodium azide

Storage

DR3 peptide is supplied as 200 μg/ml, 50 μg/vial, in PBS pH7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide. Store at -20˚C, stable for one year.

Species Reactivity

n/a

Species

H

Short Description

(ED) DR3 peptide

This product belongs to the following categories:

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References

  1. Liu X, Zou H, Slaughter C, Wang X. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 1997;89:175-184
  2. Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A, Nagata S. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 1998;391:43-50
  3. Sakahira H, Enari M, Nagata S. Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 1998;391:96-99
  4. Liu X, Li P, Widlak P, Zou H, Luo X, Garrard WT, Wang X. The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis. Proc Natl Acad Sci USA 1998;95:8461-6


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