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Primary Antibodies
CDC25C Antibody
Background
CDC25C; cell division cycle 25C protein, isoform b; mitosis inducer CDC25; phosphotyrosine phosphatase; m-phase inducer phosphatase 3; dual specificity phosphatase CDC25C. CDC25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest.
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Description
CDC25C2 IgY Antibody
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Location
The gene that codes for this protein is at chromosomal location 5q31.
Purification
Antigen affinity-purified
Clonality / Clone
This is a polyclonal antibody.
Host
CDC25C antibody was raised in chicken.
Please use anti-chicken secondary antibodies.
Immunogen
351-400
Application
CDC25C2 antibody can be used for the detection of CDC25C2 by Western blot, may also work for IHC and ICC.
Tested Application
WB
Buffer
Phosphate-Buffered Saline. No preservatives added.
Storage
CDC25C antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Species Reactivity
H
Protein GI Number
12408658
Protein Accession Number
NP_073720.1
Molecular Weight
53.3 kDa (calculated)
Short Description
Cell division cycle 25C protein, isoform b
This product belongs to the following categories:
References- Bulavin,D. V., et al. Dual phosphorylation controls Cdc25 phosphatases and mitotic entry. Nat. Cell Biol. 5 (6), 545-551 (2003)
Datasheet 0801-W
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