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Catalog Number:

XW-7722


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REDI-Ladder™ Molecular Weight Marker


Antibody Production


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Primary Antibodies

CCR1 Antibody

Background

FUNCTION: Receptor for a C-C type chemokine. Binds to MIP-1-α, MIP-1-Δ, RANTES, and MCP-3 and, less efficiently, to MIP-1-β or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation.

SIMILARITY: Belongs to the G-protein coupled receptor 1 family.

SUBCELLULAR LOCATION: Membrane; multi-pass membrane protein.

Additional Names

CC chemokine receptor type 1, C-C CKR-1, CC-CKR-1, CCR-1, CCR1, Macrophage inflammatory protein 1-alpha receptor, MIP-1alpha-R, RANTES-R, HM145, LD78 receptor, CD191 antigen

Location

The gene that codes for this protein is at chromosomal location 3p21.

Purification

Immunoaffinity Purified

Clonality / Clone

This is a polyclonal antibody.

Host

CCR1 antibody was raised in chicken.

Please use anti-chicken secondary antibodies.

Immunogen

1-40

Application

C-C chemokine receptor type 1 antibody can be used for the detection of C-C chemokine receptor type 1 by Western Blot.

Tested Application

WB

Buffer

Phosphate-Buffered Saline. No preservatives added.

Storage

CCR1 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Species Reactivity

H

Protein GI Number

4502631

Protein Accession Number

NP_001286.1

Molecular Weight

41.2 kDa (calculated)

Short Description

C-C chemokine receptor type 1

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