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Primary Antibodies
CCL4 Antibody
Background
FUNCTION: Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T cells. Recombinant MIP-1-β induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-β(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T cells. MIP-1-β(3-69) is also a ligand for CCR1 and CCR2 isoform B.
Additional Names
Small inducible cytokine A4, CCL4, Macrophage inflammatory protein 1-beta, MIP-1-beta, MIP-1-beta(1-69), T-cell activation protein 2, ACT-2, PAT 744, H400, SIS-gamma, Lymphocyte activation gene 1 protein, LAG-1, HC21, G-26 T lymphocyte-secreted protein
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Description
Left: Recombinant protein as test antigen. Rabbit polyclonal anti-MIP 1b IgG as capture antibody, Affinity-Purified MIP 1b IgY-Biotin as detection antibody.
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Location
The gene that codes for this protein is at chromosomal location 17q12.
Purification
Immunoaffinity Purified
Clonality / Clone
This is a polyclonal antibody.
Host
CCL4 antibody was raised in chicken.
Please use anti-chicken secondary antibodies.
Immunogen
27-92
Application
Small inducible cytokine A4 antibody can be used for the detection of Small inducible cytokine A4 by ELISA and Western Blot, may also work for ICC and IHC.
Tested Application
E, WB
Buffer
Phosphate-Buffered Saline. No preservatives added.
Storage
CCL4 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Species Reactivity
H
Protein GI Number
4506845
Protein Accession Number
NP_002975.1
Molecular Weight
10.2 kDa (calculated)
Short Description
Macrophage inflammatory protein 1-b
This product belongs to the following categories:
Datasheet 0801-W
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