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Primary Antibodies
BAP3 Antibody
Background
BRAL1 is a member a superfamily consisting of several highly homologous hyaluronan and proteoglycan binding link proteins. BRAL1 is predominantly expressed in brain tissue and spinal cord. Like other members in the link-module superfamily, BRAL1 contains an immunoglobulin-like fold and two proteoglycan tandem repeats (PTRs). Its mRNA expression pattern is similar to other lectican proteoglycans, suggesting that BRAL1 may act to stabilize the binding between the extracellular matrix molecule hyaluronan and brevican. Immunostaining of mouse brain showed BRAL1 expression at P20 in the white matter of the developing cerebellum and in myelinated fiber tracts in the adult brain, suggesting that expression starts when axonal myelination occurs.
Additional Names
BAP3 (NT), BAI1-associated protein 3, BAIAP3
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Description
Left: Western blot analysis of BAP3 in SK-N-SH cell lysate with BAP3 antibody at 2 μg/ml.
Below: Immunohistochemical staining of human brain tissue using BAP3 antibody at 2.5 μg/ml.
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Other Product Images
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Source
BAP3 antibody was raised against a 12 amino acid peptide from near the amino terminus of human BAP3.
Purification
Affinity chromatography purified via peptide column
Clonality / Clone
This is a polyclonal antibody.
Host
BAP3 antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
Application
BAP3 antibody can be used for the detection of BAP3 by Western blot at 2 μg/ml.
Tested Application
E, WB, IHC
Buffer
Antibody is supplied in PBS containing 0.02% sodium azide.
Blocking Peptide
Cat.No. 4503P - BAP3 Peptide
Storage
BAP3 antibody can be stored at 4˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Positive Control
- Cat. No. 1220 - SK-N-SH Cell Lysate
Species Reactivity
H
Protein GI Number
3929917
Protein Accession Number
BAA34710
Short Description
(NT) BAI1-associated protein 3
This product belongs to the following categories:
Related Products
References- Shiratsuchi T, Oda K, Nishimori H, et al. Cloning and characterization of BAP (BAI-associated protein 3), a C2 domain-containing protein that interacts with BAI1. Biochem. Biophys. Res. Comm. 1998; 251:158-65.
- Palmer RE, Lee SB, Wong JC, et al. Induction of BAIAP3 by the EWS-WT1 chimeric fusion implicates regulated exocytosis in tumorigenesis. Cancer Cell 2002; 2:497-505.
Datasheet 08-02W
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