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Primary Antibodies
Aurora Kinase B Antibody
Background
Aurora Kinase B (also known as Aurora- and Ipl1-like midbody-associated protein 1, AIM-1, Aurora/IPL1-related kinase 2, Aurora-related kinase 2, STK-1, and Aurora-B) is a Ser/Thr protein kinase member of the Aurora subfamily that may be directly involved in regulating the cleavage of polar spindle microtubules and is a key regulator for the onset of cytokinesis during mitosis. Aurora Kinase B is localized to the midzone of central spindle in late anaphase and concentrated into the midbody in telophase and cytokinesis and is colocalized with gamma tubulin in the mid-body. High levels of Aurora B expression are seen in the thymus, although it is also expressed in the spleen, lung, testis, colon, placenta and fetal liver. Aurora B is expressed during S and G2/M phase and expression is up-regulated in cancer cells during M phase.
Additional Names
AURKB, AIK2, AIM-1, AIM1, ARK2, AURB, AURORA-B, EC 2.7.11.1, IPL1, STK-1, STK12, STK5, AIRK2, Aurora-B, aurora-related kinase 2, AURORA/IPL1-LIKE KINASE 2, Aurora1, Serine/threonine protein kinase 12
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Description
Left: Immunohistochemistry staining of Aurora Kinase B in spleen (formalin-fixed paraffin-embedded) using Aurora Kinase B antibody.
Below: Immunohistochemistry staining of Aurora Kinase B in spleen (formalin-fixed paraffin-embedded) using Aurora Kinase B antibody.
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Other Product Images
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Purification
Immunoaffinity Chromatography
Clonality / Clone
This is a polyclonal antibody.
Host
Aurora Kinase B antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
Immunogen
Aurora Kinase B antibody was raised against aa 227-238 of Aurora Kinase B. (Human)
Application
Aurora Kinase B antibody can be used for detection of Aurora Kinase B by WB (1:500 - 1:2000), ELISA (1:5000 - 1:20000), IF, IHC-parafin (5 μg/ml).
Tested Application
E, WB, IHC, IF
Buffer
Aurora Kinase B antibody is supplied in 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
Storage
Aurora Kinase B antibody can be stored at 4˚C or -20˚C, Avoid repeated freezing and thawing.
Species Reactivity
H
Formulation
Weight: 50 μg
Concentration: 1.2 mg/ml
Short Description
Aurora Kinase B
This product belongs to the following categories:
Datasheet 09-01W
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