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Primary Antibodies
ATP7A Antibody
Background
ATPase, Copper-transporting, α polypeptide; Copper-transporting ATPase 1. Copper-transporting ATPase 1 is an integral membrane protein cycling constitutively between the trans-golgi network and the plasma membrane. It may supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells.
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Description
ATP7A IgY Antibody
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Location
The gene that codes for this protein is at chromosomal location Xq13.2-q13.3.
Purification
Antigen affinity-purified
Clonality / Clone
This is a polyclonal antibody.
Host
ATP7A antibody was raised in chicken.
Please use anti-chicken secondary antibodies.
Immunogen
1407-1500
Application
ATP7A antibody can be used for the detection of ATP7A by Western blot, may also work for IHC and ICC.
Tested Application
WB
Buffer
Phosphate-Buffered Saline. No preservatives added.
Storage
ATP7A antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Species Reactivity
H, M, R
Protein GI Number
4502321
Protein Accession Number
NP_000043.1
Molecular Weight
163.3 kDa (calculated)
Short Description
ATPase, Copper-transporting, a polypeptide
This product belongs to the following categories:
References- Vulpe,C., Levinson,B., Whitney,S., Packman,S. and Gitschier,J. Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper-transporting ATPase Nat. Genet. 3 (1), 7-13 (1993).
Datasheet 0801-W
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