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Primary Antibodies
ATG5 Antibody
Background
ATG5 is required for the process of autophagy, an intracellular process for bulk degradation of cytoplasmic components. ATG5 conjugates to ATG12 and associates with isolation membranes to form autophagosomes. The autophagosomes then enclose cytoplasmic components and deliver them to lysosomes/vacuoles to be degraded. ATG5 has been shown to be involved in apoptosis with expression late in the apoptotic process downstream of caspase activity.
Additional Names
ATG5, APG5, APG5-LIKE, APG5L, ASP, HAPG5
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Description
Left: Immunohistochemistry staining of ATG5 in kidney (formalin-fixed paraffin-embedded) using ATG5 antibody.
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Purification
Immunoaffinity Chromatography
Clonality / Clone
This is a polyclonal antibody.
Host
ATG5 antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
Immunogen
ATG5 antibody was raised against a portion of amino acid 1-50 of ATG5. (Human)
Application
ATG5 antibody can be used for detection of ATG5 by WB (0.5 - 2 μg/ml), IHC-parafin (5 μg/ml).
Tested Application
WB, IHC
Buffer
ATG5 antibody is supplied in PBS, 0.2% gelatin, 0.05% sodium azide.
Storage
ATG5 antibody can be stored at 4˚C for short term storage, for long term storage aliquot and store at -20˚C . Avoid freeze thaw cycles.
Species Reactivity
M, R, B, P, PF, ZF
Formulation
Weight: 50 μg
Concentration: 0.5 mg/ml
Short Description
ATG5 Autophagy Related 5 Homolog
This product belongs to the following categories:
Datasheet 09-01W
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