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Catalog Number:

3677P


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REDI-Ladder™ Molecular Weight Marker


Antibody Production


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Peptides

ASK1 Peptide (C2)

Background

ASK1 Peptide (C2)

Location

16 amino acids near the carboxy terminus of human ASK1.

Application

ASK1 peptide (C2) is used for blocking the activity of ASK1 antibody (Cat. No. 3677). It usually blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37˚C. For research use only.

Tested Application

Bl

Buffer

PBS containing 0.02% sodium azide

Storage

ASK1 peptide(C2) is supplied as 200 μg/ml, 50 μg/vial, in PBS pH7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide. Store at -20˚C, stable for one year.

Species Reactivity

n/a

Species

H

Short Description

(C2) ASK1 peptide

This product belongs to the following categories:

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References

  1. Wang XS, Diener K, Jannuzzi D, et al. Molecular cloning and characterization of a novel protein kinase with a catalytic domain homologous to mitogen-activated protein kinase kinase kinase. J. Biol. Chem. 1996; 271:31607-11.
  2. van Kooten C and Bancherau J. CD40-CD40 ligand. J. Leukoc. Biol. 2000; 67:2-17.
  3. Grech AP, Amesbury M, Chan T, et al. TRAF2 differentially regulates the canonical and noncanonical pathways of NF-κB activation in mature B cells. Immunity 2004; 21:629-42.
  4. Davies CC, Mak TW, Young LS, et al. TRAF6 is required for TRAF2-dependent CD40 signal transduction in nonhemopoietic cells. Mol. Cell. Biol. 2005; 25:9806-19. 5. Kuai J, Nickbarg E, Wooters J, et al. Endogenous association of TRAF2, TRAF3, cIAP1, and Smac with lymphotoxin-? receptor reveals a novel mechanism of apoptosis. J. Biol. Chem. 2003; 278:14363-9.


Datasheet 0801-W

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