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Primary Antibodies
APEX Nuclease Antibody
Background
Apurinic/apyrimidinic (AP) sites occur frequently in DNA by spontaneous hydrolysis, DNA damaging agents or DNA glycosylases that remove specific abnormal bases. ClassII AP endonucleases act to repair this damage by cleaving the phosphodiester backbone. It is primarily located in the nucleus but is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair (BER).
Additional Names
APEX2, APE2, APEXL2, DNA-, EC 4.2.99.18, XTH2, apexl2
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Description
Left: Immunohistochemistry staining of APEX Nuclease in breast (formalin-fixed paraffin-embedded) using APEX Nuclease antibody.
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Purification
Protein G Column
Clonality / Clone
This is a polyclonal antibody.
Isotype
IgG
Host
APEX Nuclease antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
Immunogen
APEX Nuclease antibody was raised against synthetic peptides of APEX Nuclease. (Human)
Application
APEX Nuclease antibody can be used for detection of APEX Nuclease by WB (1:500 - 1:1000), IHC-parafin (10 μg/ml).
Tested Application
WB, IHC
Buffer
APEX Nuclease antibody is supplied in PBS, 0.02% sodium azide.
Storage
APEX Nuclease antibody can be stored at 4˚C for short term storage. For long term storage, aliquot and store at -20˚C.
Species Reactivity
H
Formulation
Volume: 50 μl
Short Description
APEX Nuclease 2
This product belongs to the following categories:
Datasheet 09-01W
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