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Primary Antibodies
APC Antibody
Background
APC is associated with structural components of intracellular junctions, including conductin, and it competes with E-cadherin for binding to specific internal regions of both - and -catenin. Like APC, APC2 contains SAMP domains, which are required for conductin binding. Both APC and APC2 regulate the formation of active -catenin-Tcf complexes.
Additional Names
APC, adenomatous polyposis coli protein, apc, apc tumor suppressor gene, dp2, dp2.5, DP3, FAP, fpc, gs
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Description
Left: Immunohistochemistry staining of APC in normal colon using APC antibody.
Below: Immunohistochemistry staining of APC in colon (formalin-fixed paraffin-embedded) using APC antibody.
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Other Product Images
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Purification
Immunoaffinity Chromatography
Clonality / Clone
This is a polyclonal antibody.
Host
APC antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
Immunogen
APC antibody was raised against a synthetic peptide derived from C-terminus of human APC protein. (Human)
Application
APC antibody can be used for detection of APC by WB, IP, IHC-parafin (10 μg/ml).
Tested Application
WB, IHC, IP
Buffer
APC antibody is supplied in 10 mM PBS, pH 7.4, BSA, sodium azide.
Storage
APC antibody can be stored at 4˚C or -20˚C. Avoid repeated freezing and thawing.
Species Reactivity
M, R
Formulation
Weight: 50 μg
Short Description
Adenomatous Polyposis Coli Protein
This product belongs to the following categories:
Datasheet 09-01W
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