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Primary Antibodies
AP3S2 Antibody
Background
FUNCTION: Part of the AP-3 complex, an adapter-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.
SUBUNIT: Adapter protein complex 3 (AP-3) is an heterotetramer composed of two large adaptins (Δ/AP3D1 and β3A/AP3B2 or β3B/AP3B1), a medium adaptin (mu3A/AP3M1 or mu3B/AP3M2) and a small adaptin (Σ3A/AP3S1 or Σ3B/AP3S2). Interacts with CENTG2 (By similarity).
Additional Names
AP3 complex subunit sigma2, Adapter-related protein complex 3 sigma-2 subunit, Sigma-adaptin 3b, AP-3 complex sigma-3B subunit, Sigma-3B-adaptin
Location
The gene that codes for this protein is at chromosomal location 15q26.1.
Purification
Immunoaffinity Purified
Clonality / Clone
This is a polyclonal antibody.
Host
AP3S2 antibody was raised in chicken.
Please use anti-chicken secondary antibodies.
Immunogen
1-193
Application
AP3S2 antibody can be used for the detection of AP-3 complex subunit Σ-2 by Western Blot.
Tested Application
WB
Buffer
Phosphate-Buffered Saline. No preservatives added.
Storage
AP3S2 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Species Reactivity
H, M
Protein GI Number
5031581
Protein Accession Number
NP_005820.1
Molecular Weight
22 kDa (calculated)
Short Description
Adapter-related protein complex 3 Σ-2 subunit
This product belongs to the following categories:
Related Products
Datasheet 0801-W
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