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Primary Antibodies
AKT2 Antibody
Background
Murine thymoma viral (v-akt) homolog-2; rac protein kinase β. AKT2 is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. Furthermore, AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.
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Description
AKT2 IgY Antibody
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Location
The gene that codes for this protein is at chromosomal location 19q13.1-q13.2.
Purification
Antigen affinity-purified
Clonality / Clone
This is a polyclonal antibody.
Host
AKT2 antibody was raised in chicken.
Please use anti-chicken secondary antibodies.
Immunogen
108-124
Application
AKT2 antibody can be used for the detection of AKT2 by Western blot, ELISA, may also work for IHC and ICC.
Tested Application
E
Buffer
Phosphate-Buffered Saline. No preservatives added.
Storage
AKT2 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Species Reactivity
H
Protein GI Number
4502023
Protein Accession Number
NP_001617.1
Molecular Weight
55.8 kDa (calculated)
Short Description
V-akt murine thymoma viral oncogene homolog 2
This product belongs to the following categories:
Related Products
References- Cheng, J. Q., Ruggeri, B., Klein, W. M., Sonoda, G., Altomare, D. A., Watson, D. K., Testa, J. R. Amplification of AKT2 in human pancreatic cancer cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA. Proc. Nat. Acad. Sci. 93: 3636-3641, 1996.
Datasheet 0801-W
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