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Primary Antibodies
ADRB2 Antibody
Background
FUNCTION: β-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The β-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
DISEASE: Polymorphic forms of ADRB2 could impart some form of nocturnal asthma.
SUBUNIT: Binds SLC9A3R1.
PTM: Phosphorylated by PKA and BARK; mediate homologous desensitization of the receptor. PKA-mediated phosphorylation seems to facilitate phosphorylation by BARK
Additional Names
b2 adrenergic receptor, Beta-2 adrenoceptor, Beta-2 adrenoreceptor
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Description
Left: E coli-derived fusion protein as test antigen. Affi-pure IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
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Location
The gene that codes for this protein is at chromosomal location 5q31-q32.
Purification
Immunoaffinity Purified
Clonality / Clone
This is a polyclonal antibody.
Host
ADRB2 antibody was raised in chicken.
Please use anti-chicken secondary antibodies.
Immunogen
335-408
Application
β-2 adrenergic receptor antibody can be used for the detection of β-2 adrenergic receptor by Western Blot.
Tested Application
WB
Buffer
Phosphate-Buffered Saline. No preservatives added.
Storage
ADRB2 antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Species Reactivity
H
Protein GI Number
4501969
Protein Accession Number
NP_000015.1
Molecular Weight
46.6 kDa (calculated)
Short Description
b-2 adrenergic receptor, b-2 adrenoceptor, b-2 adrenoreceptor
This product belongs to the following categories:
Related Products
Datasheet 0801-W
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