|
Primary Antibodies
ACVR1 Antibody
Background
ACVR1 Antibody.
Additional Names
ACVR1, activin A receptor, type I, ACTRI, ACVRLK2, ALK2, FOP, SKR1, activin A receptor, type II-like kinase 2, activin A type I receptor, hydroxyalkyl-protein kinase
|
Description
Left: Western blot analysis of ACVR1 in human umbilical cord lysate (35μg protein in RIPA buffer) using ACVR1 antibody (0.3μg/mL).
Below: Immunocytochemistry of ACVR1 in paraffin embedded human testis using ACVR1 antibody (4μg/mL).
|
|
Other Product Images
|
Source
ACVR1 antibody was raised against a synthetic peptide of ACVR1.
Purification
ACVR1 antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Clonality / Clone
This is a polyclonal antibody.
Host
ACVR1 antibody was raised in goat.
Please use anti-goat secondary antibodies.
Application
Peptide ELISA: antibody detection limit dilution 1:128000. Western Blot: Approx 60kDa band observed in Human Umbilical Cord lysates (calculated MW of 57.2kDa according to NP_001096.1). Recommended concentration: 0.3-1μg/ml. Immunohistochemistry: In paraffin embedded Human Testis shows preferential staining of cytoplasm in primary spermatocytes.. Recommended concentration, 4-6μg/ml.
Tested Application
E, WB, IHC
Buffer
ACVR1 antibody is supplied as 0.1mg of purified antibody, 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Blocking Peptide
Cat. No. 45-201P - ACVR1 Peptide
Storage
Aliquot and store at -20°C. Minimize freezing and thawing.
Species Reactivity
H, M, R, D
Protein Accession Number
NP_001096.1
Short Description
ACVR1
This product belongs to the following categories:
Related Products
References- Shore EM, Xu M, Feldman GJ, Fenstermacher DA, Cho TJ, Choi IH, Connor JM, Delai P, Glaser DL, LeMerrer M, Morhart R, Rogers JG, Smith R, Triffitt JT, Urtizberea JA, Zasloff M, Brown MA, Kaplan FS. A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva. Nat Genet. 2006 May;38(5):525-7. Epub 2006 Apr 23. Erratum in: Nat Genet. 2007
Datasheet 08-01W
|
|
