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Primary Antibodies
ABCC4 Antibody
Background
Although increased levels of Pgp are likely to contribute to MDR in at least some tumor types, it has become evident that alternative, non-Pgp-mediated mechanisms of MDR exist. The multidrug resistance-associated protein (MRP1) has been identified by Cole and Deeley. The amino acid identity between MRP1 and Pgp is only 15%, and the homology to chloride channel CFTR only 19%. Paulusma, et al., cloned the cDNA for rat canalicular multispecific organic anion transporter (cMOAT or MRP2) which turned out to be a novel liver specific homolog of human MRP1. Recently, by screening database of human expressed sequences tags, Kool identified three new homologs of MRP1, called MRP3, MRP4 and MRP5. Suitable for use in Immunohistochemistry and Western Blot. Other applications have not been tested. Recognizes human MRP4. Does not recognize other species.
Additional Names
ABCC4, Abcc4, ATP-binding cassette sub-family C member 4, canalicular multispecific organic anion transporter, EST170205, MOAT-B, MOATB, MRP4, multidrug resistance protein 4, multidrug resistance-associated protein 4, multispecific organic anion transporter B
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Description
Left: Immunohistochemistry staining of ABCC4 in prostate (formalin-fixed paraffin-embedded) using ABCC4 antibody.
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Purification
Affinity Chromatography
Clonality / Clone
This is a polyclonal antibody.
Isotype
IgG
Host
ABCC4 antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
Immunogen
ABCC4 antibody was raised against a recombinant peptide corresponding to aa 1249-1268 of human ABCC4. (Human)
Application
ABCC4 antibody can be used for detection of ABCC4 by IHC, WB (1:500), IHC-parafin (1:100).
Tested Application
WB, IHC
Buffer
ABCC4 antibody is supplied in borate buffer, 0.05% BSA, 40% glycerol.
Storage
ABCC4 antibody can be stored at 4˚C or -20˚C. Avoid repeated freezing and thawing.
Species Reactivity
n/a
Formulation
Volume: 50 μl
Short Description
ATP-Binding Cassette, Sub-Family C
This product belongs to the following categories:
Datasheet 09-01W
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