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Primary Antibodies
AASDHPPT Antibody
Background
AASDHPPT is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.
Additional Names
AASDHPPT, AASD-PPT, CGI-80, DKFZp566E2346, LYS2, LYS5
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Description
Left: Western blot analysis of AASDHPPT in HepG2 Cell Lysate using AASDHPPT antibody at 0.25 μg/ml (12% gel). Marker in lane A.
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Purification
Antibody is purified by peptide affinity chromatography method.
Clonality / Clone
This is a polyclonal antibody.
Host
AASDHPPT antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AASDHPPT.
Application
AASDHPPT antibody can be used for detection of AASDHPPT by ELISA at 1:12500. AASDHPPT antibody can be used for detection of AASDHPPT by western blot at 0.25 μg/ml, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Tested Application
E, WB
Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μl of distilled water. Final antibody concentration is 1 mg/ml.
Storage
For longer periods of storage, store AASDHPPT antibody at -20˚C. Avoid repeat freeze-thaw cycles.
Species Reactivity
H
Protein Accession Number
NP_056238
Molecular Weight
36kDa
Short Description
AASDHPPT (aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase)
This product belongs to the following categories:
References- Joshi,A.K., (2003) J. Biol. Chem. 278 (35), 33142-33149.
Datasheet 10-01W
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