Datasheet

Prion Protein Antibody
CATALOG NUMBER: 45-123

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Specifications
Properties
Additional Info
Background

Specifications

SPECIES REACTIVITY:Human
TESTED APPLICATIONS:ELISA, WB
APPLICATIONS:ELISA: antibody detection limit dilution 1:64000. Western Blot: Approx 25kDa band observed in Human Brain lysates (calculated MW of 27.7kDa according to NP_000302.1 and NP_898902.1). Recommended concentration: 0.3-1μg/ml.
POSITIVE CONTROL:1) Cat. No. 1303 - Human Brain Tissue Lysate
SPECIFICITY:Reported variants represent identical protein (NP_000302.1; NP_898902.1; NP_001073590.1; NP_001073591.1; NP_001073592.1).
IMMUNOGEN:Prion Protein antibody was raised against an 11 amino acid synthetic peptide near the internal region of Prion Protein.
HOST SPECIES:Goat

Properties

PURIFICATION:Prion Protein antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
PHYSICAL STATE:Liquid
BUFFER:Prion protein antibody is supplied in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.
CONCENTRATION:500 ug/mL
STORAGE CONDITIONS:Aliquot and store at -20˚C. Minimize freezing and thawing.
CLONALITY:Polyclonal
CONJUGATE:Unconjugated

Additional Info

ALTERNATE NAMES:PRNP, prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia), ASCR, CD230, CJD, GSS, MGC26679, PRIP, PrP, PrP27-30, PrP33-35C, PrPc, CD230 antigen, major prion protein, prion protein, prion protein (p27-30) (Creutzfeld-Jakob disease Gerstmann-Strausler-Scheinker syndrome, prion protein PrP, prion-related protein , KURU, AltPrP, p27-30
ACCESSION NO.:NP_000302.1, NP_898902.1
PROTEIN GI NO.:4506113
OFFICIAL SYMBOL:PRNP
GENE ID:5621

Background

REFERENCES: 1) Ballerini C, Gourdain P, Bachy V, Blanchard N, Levavasseur E, Gregoire S, Fontes P, Aucouturier P, Hivroz C, Carnaud C. Functional Implication of Cellular Prion Protein in Antigen-Driven Interactions between T Cells and Dendritic Cells. J Immunol. 2006 Jun 15;176(12):7254-62.

For Research Use Only