Antigen Design Assistance

ProSci Antigen Design Assistance

 

ProSci's quality antigen design services include complimentary antigen design assistance for peptide antigens. If you can provide us with the sequence (or protein accession number), our scientists will analyze your protein and select the regions which offer the best chance of eliciting an immune response for a variety of applications, including western blot, immunohistochemistry, immunocytochemistry, and immunoprecipitation. We base our sequence analysis on several factors:

Structural


Predicted number of turns
Predicted hydrophilicity
Predicated antigenicity

Sequence


Conjugation-method constraints
Amino acid composition
Presence of potential post-translational modification

The ProSci Guarantee

If you choose to use a sequence we have designed or approved for one of our standard antibody production packages utilizing peptide synthesis, we will guarantee the immune response against the peptide antigen. If no titer is observed, ProSci will re-immunize a new set of animals. If a titer against the antigen is still not present, ProSci will re-evaluate the protein of interest and synthesize a new peptide at no cost. ProSci will continue to work on your project until a successful immune response is observed.

Your Custom Antibody Experts

To take advantage of this service please fill out the Antigen Design Form with any applicable sequence information, and email it to abservices@prosci-inc.com. This will allow us to design peptide sequences based on your specific homology or application constraints.

Alternatively, if you simply need full-sequence suggestions you can e-mail your full length protein sequence(s) to abservices@prosci-inc.com and a ProSci representative will respond with our selections in 2 to 3 working days.

If you have any questions regarding our antigen design assistance service please contact us at abservices@prosci-inc.com, or by calling toll-free 888-513-9525.