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May 2017 Antibody UpdateMay 2017: The Antibody Update

In the May 2017 Antibody Update, ProSci presents to you a virucidal peptide found in the skin of frogs, evidence of new and hopeful RNA-drugs, and the innate immune systems role in congenital autoimmunity. 


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Friday, May 5, 2017 12:17:25 PM America/Los_Angeles
Posted in News By Yousif Slaiwa

Antibody Basics: Selecting AntigensAntibody Basics: Selecting Antigens

Selecting the proper antigen is paramount for assuring  the development of desired antibodies; however, the proper antigen must still maintain immunoreacivity in order to develop antibodies. This dilemma can be solved for for several antigens. In this blog we discuss targeting glycosylated proteins and highly conserved mammalian proteins for antibody development.

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Monday, May 1, 2017 10:19:33 AM America/Los_Angeles
Posted in Science Corner By Jonathan Felix

March 2017 Antibody UpdateMarch 2017: The Antibody Update

This month the Antibody Update showcases caffeine as a potential anti-inflammatory agent, how mTOR is related to granuloma formation, and a retinal transplant using induced pluripotent stem cells. Learn more here!


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Friday, March 31, 2017 10:00:00 AM America/Los_Angeles
Posted in News By Yousif Slaiwa

February 2017 Antibody UpdateFebruary 2017: The Antibody Update

This month's Antibody Update includes news on how your skin bacteria regulate levels of Staphylococus aureus, a new study using single cell sequence analysis to create 3D models of tumor tissue, and development of chimeric antigen receptor T-cells using CRISPR/Cas9 to enhance immunotherapy.

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Monday, March 6, 2017 12:11:46 PM America/Los_Angeles
Posted in News By Jonathan Felix

ProSci Blog Personalized MedicineProblems with Immunotherapy

Immune system checkpoint inhibition may not always be the perfecct way to target cancer. Why is it that some patients do not respond positively to certain immunotherapy treatments like Ipilimumab? This blog takes into account the immune system's convoluted nature to understand how immune checkpoint antibodies may not be the problem, and how personalized medicine could help.

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Wednesday, February 15, 2017 10:00:00 AM America/Los_Angeles
Posted in Science Corner By Yousif Slaiwa

January 2017 Antibody UpdateJanuary 2017: The Antibody Update

The start of the new year has brought some interesting new stories in science and science policy. This Antibody Update looks at The Reproducibility Project's efforts in cancer drug research, changes to encourage vaccine development against less known, but still threatening viruses, and a new study on the mechanism of how macrophages cross the vascular endothelium.

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Monday, February 6, 2017 9:09:09 AM America/Los_Angeles
Posted in News By Jonathan Felix

T-cell Activation ProSci BlogT-cell Activation: The Purpose of CD28, CTLA-4, and CD80/CD86 

Cancer immunotherapy involves targeting receptors and ligands of T-cells and tumor cells to amplify an immune response. By targeting these receptors and ligands, T-cell anti-cancer activity can be regulated. This blog explains how the receptors CD28 and CTLA-4 and their ligands CD80 and CD86 are involved in T-cell activation and inhibition. Take a look!

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Tuesday, January 17, 2017 10:00:00 AM America/Los_Angeles
Posted in Science Corner By Jonathan Felix

November 2016 Antibody UpdateDecember 2016: The Antibody Update

ProSci's last Antibody Update of 2016 includes the super effective Ebola vaccine developed by Merck, using the common diabetes drug metformin and the antihypertensive syrosingopine to combat cancer, and a link to a highlight review of the immune checkpoint TIGIT. Check it out!

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Tuesday, January 3, 2017 10:00:00 AM America/Los_Angeles
Posted in News By Jonathan Felix

October 2016 Antibody UpdateNovember 2016: The Antibody Update

This months Antibody Update features the first use of CRISPR-Cas9 modified cells being used as therapeutics, the launch of the first vaccine against malaria, and the 21st Century Cures act, which may vastly increase funding of public health agencies for the next decade. Learn more here.

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Wednesday, November 30, 2016 10:30:41 AM America/Los_Angeles
Posted in News By Jonathan Felix

Bacterial vs. Mammalian Expression Systems

Bacterial vs. Mammalian Expression Systems

This blog focuses on the differences between bacterial and mammalian cell expression systems. E. coli make excellent organisms for expression of several types of proteins, but do have limitations based on their cellular hardware. This is where mammalian cells can really shine, creating more native, natural proteins and effective antibodies. Learn more here!

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Monday, November 21, 2016 9:08:39 AM America/Los_Angeles
Posted in Science Corner By Jonathan Felix
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