Datasheet

AIG1 Antibody
CATALOG NUMBER: 6785

Availability: In stock

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Specifications
Properties
Additional Info
Background

Specifications

SPECIES REACTIVITY:Human, Mouse, Rat
TESTED APPLICATIONS:ELISA, IF, IHC-P, WB
APPLICATIONS:AIG1 antibody can be used for detection of AIG1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 2.5 μg/mL.
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
POSITIVE CONTROL:1) Cat. No. 1303 - Human Brain Tissue Lysate
 2) Cat. No. 10-301 - Human Brain Tissue Slide
IMMUNOGEN:AIG1 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human AIG1.

The immunogen is located within amino acids 50 - 100 of AIG1.
HOST SPECIES:Rabbit

Properties

PURIFICATION:AIG1 Antibody is affinity chromatography purified via peptide column.
PHYSICAL STATE:Liquid
BUFFER:AIG1 Antibody is supplied in PBS containing 0.02% sodium azide.
CONCENTRATION:1 mg/mL
STORAGE CONDITIONS:AIG1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated

Additional Info

ALTERNATE NAMES:AIG1 Antibody: AIG-1, dJ95L4.1, Androgen-induced gene 1 protein, AIG-1
ACCESSION NO.:NP_057192
PROTEIN GI NO.:40316941
OFFICIAL SYMBOL:AIG1
GENE ID:51390

Background

BACKGROUND:AIG1 Antibody: Androgen-induced 1 (AIG1) is a novel Pirh2-interacting protein, which was initially cloned from human dermal papilla cells and is evolutionally conserved from drosophila through to humans. It is a membrane protein and belongs to the protein family containing FAR-17a domain. AIG1 may play a role in androgen-regulated growth of hair follicles. AIG1 could serve as a new biomarker for the diagnosis and prognostic evaluation of HCCs and may be a novel candidate tumor suppressor.
REFERENCES: 1) Wu G, Sun M, Zhang W, et al. AIG1 is a novel Pirh2-interacting protein that activates the NFAT signaling pathway. Front. Biosci. (Elite Ed). 2011; 3:834-42.
2) Seo J, Kim J, and Kim M. Cloning of androgen-inducible gene 1 (AIG1) from human dermal papilla cells. Mol. Cells 2001; 11:35-40.

For Research Use Only