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TGFB1 Monoclonal Antibody | catalog# 49-471

Background

TGFB is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGFB acts synergistically with TGFA in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGFB activation and signaling may result in apoptosis. Many cells synthesize TGFB and almost all of them have specific receptors for this peptide. It plays an important role in bone remodeling. It is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation, and differentiation in committed osteoblasts.

Description
TGFB1 Monoclonal Antibody
Immunohistochemistry staining of TGFB1 in brain tissue using TGFB1 monoclonal Antibody.
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Specifications

Additional Names
TGFB1, CED, DPD1, TGF-BETA-1, TGFB, diaphyseal dysplasia 1, transforming growth factor beta 1
Conjugate
None
Formulation
Weight: 50 μg
Volume: 50 μl
Concentration: 1 mg/ml
Disclaimer
This product is for research use only.
Clonality/Clone
This is a monoclonal antibody. (Clone TB21)
Purification
Affinity Chromatography
Host
TGFB1 monoclonal antibody was raised in mouse.

Please use anti-mouse secondary antibodies.
Immunogen
TGFB1 monoclonal antibody was raised against amino acids 780 - 797 of TGFB1 (Human).
Application
TGFB1 antibody can be used in ELISA, and immunohistochemistry starting at 15 - 30 μg/mL.
Tested Application
E, IHC, FACS
Buffer
PBS, 0.09% sodium azide.
Storage
Store TGFB1 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Species Reactivity
H