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TADA2L Antibody | catalog# 25-406

Background

Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. TADA2L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex.Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Two transcript variants encoding different isoforms have been identified for this gene.

Description
TADA2L Antibody
Western blot analysis of TADA2L in Jurkat cell lysate using TADA2L antibody at 1 μg/ml (12% gel).
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Specifications

Additional Names
TADA2L, ADA2, FLJ12705, KL04P, hADA2
Positive Control
  • Cat. No. 1205 - Jurkat Cell Lysate]
Disclaimer
This product is for research use only.
Clonality/Clone
This is a polyclonal antibody.
Purification
Antibody is purified by peptide affinity chromatography method.
Host
TADA2L antibody was raised in rabbit.

Please use anti-rabbit secondary antibodies.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TADA2L.
Application
TADA2L antibody can be used for detection of TADA2L by ELISA at 1:312500. TADA2L antibody can be used for detection of TADA2L by western blot at 1 μg/ml, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Tested Application
E, WB
Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μl of distilled water. Final antibody concentration is 1 mg/ml.
Storage
For short periods of storage (days) store at 4˚C. For longer periods of storage, store TADA2L antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Species Reactivity
H
Protein Accession Number
NP_597683
Molecular Weight
36 kDa
Reference
  1. Yang, M., (2008) Cancer Biol. Ther. 7 (1), 120-128.]