OPRK1 Antibody | catalog# 27-232
Background
OPRK1 is a multi-pass membrane protein. It belongs to the G-protein coupled receptor 1 family. OPRK1 inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. It is the receptor for dynorphins. OPRK1 may play a role in arousal and regulation of autonomic and neuroendocrine functions.
Description
Western blot analysis of OPRK1 in fetal brain lysate using OPRK1 antibody at 1 μg/ml (12% gel).
Specifications
Additional Names
OPRK1, KOR, OPRKDisclaimer
This product is for research use only.Positive Control
- Cat. No. XBL-10123 - Fetal Brain Tissue Lysate]
Clonality/Clone
This is a polyclonal antibody.Purification
Antibody is purified by peptide affinity chromatography method.Host
OPRK1 antibody was raised in rabbit.Please use anti-rabbit secondary antibodies.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human OPRK1.Application
OPRK1 antibody can be used for detection of OPRK1 by ELISA at 1:62500. OPRK1 antibody can be used for detection of OPRK1 by western blot at 1 μg/ml, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.Tested Application
E, WBBuffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μl of distilled water. Final antibody concentration is 1 mg/ml.Storage
For short periods of storage (days) store at 4˚C. For longer periods of storage, store OPRK1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.Species Reactivity
HProtein Accession Number
NP_000903Molecular Weight
43 kDaReference
- Edenberg, H.J., (2008) Hum. Mol. Genet. 17 (12), 1783-1789.]