Neurobiology is a massive area of scientific research which focuses on the structure, function, development, genetics, biochemistry, physiology, pharmacology, and pathology of the nervous system. Neurobiology is a discipline which has grown tremendously and has overlap with many other scientific disciplines. There has been increasing attention given to diseases of the nervous system recently, including diseases such as Huntington's disease, Alzheimer's disease, Multiple sclerosis, and Parkinson's disease.
ProSci offers a large selection of products for neurobiology research, including primary antibodies, protein detection sets, and tissue lysates. ProSci has a variety of Alzheimer's related tissue lysates, a Alzheimer's Disease beta-amyloid Protein Detection Set, as well as many Alzheimer's disease antibodies. Beta-site beta amyloid precursor protein cleaving enzyme (BACE) is an important neurobiology antibody. BACE splits the beta-amyloid precursor protein (APP), which initiates the formation and build up of amyloid plaques which are characteristic of Alzheimer's disease.
Focal adhesion kinase (FAK) is important in neurobiology because of its involvement in integrin signaling. FAK is important for cell spreading, differentiation, migration, cell death, and speeding up the G1 to S phase transition of the cell cycle. Additionally, p53 upregulated modulator of apoptosis (PUMA) is an important modulator of apoptosis and genotoxin induced telenaphalic neural precursor cell death.
ProSci has many neurobiology antibodies, including antibodies to the proteins mentioned here. ProSci's neurobiology antibodies include antibodies against beta-site beta amyloid precursor protein cleaving enzyme (BACE), focal adhesion kinase (FAK) and p53 upregulated modulator of apoptosis (PUMA). Additionally, we offer an Alzheimer's disease Beta-Amyloid Detection set and various Alzheimer's disease tissue lysates. ProSci antibodies and detection sets are appropriate for ELISA, western blot, and immunohistochemistry (IHC) applications as noted for each neurobiology antibody or related detection set.
|Product Name||Catalog #||App.||Reactivity||Description|
|Dab 1 (pY220) pAb Antibody||XBP-4081||WB||H, M, R, C||Dab 1 (pY220) pAb|
|Dab1 [pS491] Ab, Rabbit poly Antibody||XBP-4082||WB||H, M, R, C||Dab1 [pS491] Ab, Rabbit poly|
|Dab1 [pY198] Ab, Rabbit poly Antibody||XBP-4083||WB||H, M, R, C||Dab1 [pY198] Ab, Rabbit poly|
|DAG1 Antibody||48-780||WB, IHC||H||Dystroglycan|
|DAG1 Antibody||42-607||E, WB||H||(IN) DAG1|
|DAGLA Antibody||46-829||E, WB||H||DAGLA|
|DARPP 32 (Phospho-Phospho-Thr34) Antibody||XPS-1004||WB||H, M, R, X||DARPP-32 (Thr34) Phospho-Specific|
|DARPP 32 (Phospho-Phospho-Thr75) Antibody||XPS-1005||WB||H, M||DARPP-32 (Thr75) Phospho-Specific|
|DARPP-32 Antibody||50-201||WB||H, M, R, D, ZF, B, C, X||(NT) DARPP-32 Pan-Specific|
|DBF4B Antibody||42-344||E||H||(IN) DBF4B (aa 193-207)|
|DCLK1 Antibody||5633||E, WB, IHC, IF||H, M, R||(NT) Doublecortin kinase-like 1|
|DCLK2 Antibody||5635||E, WB, IHC||H, M, R||(CT) Doublecortin kinase-like 2|
|DCLK3 Antibody||5637||E, WB, IF||H, M||(NT) Doublecortin kinase-like 3|
|DCUN1D1 Antibody||42-547||E, WB||H||(CT) DCUN1D1|
|DDR2 Monoclonal Antibody||32-144||E, WB, IHC||H||discoidin domain receptor family, member 2|
|DISC1 Antibody||51-067||E, WB, IHC||n/a||(CT) Disrupted In Schizophrenia 1|
|DISC1 Antibody||4293||E, WB||H, M||(NT) Disrupted in schizophrenia 1|
|DISC1 Antibody||51-126||E, WB, IHC||n/a||Disrupted In Schizophrenia 1|
|DISC1 Antibody||51-068||E, WB, IHC||n/a||(CT) Disrupted In Schizophrenia 1|
|DISC1 Antibody||4295||E, WB, ICC, IF||H, M||(IN) Disrupted in schizophrenia 1|
|DKFZp434A132 Antibody||XW-7709||WB||H||PCDH21 protein|
|DLAT Antibody||XW-8135||WB||H||Dihydrolipoyllysine-residue acetyltransferase comp|
|DLG1 Antibody||46-831||E, WB||H||DLG1|
|DLL1 Antibody||26-150||E, WB||H, M, R||DLL1 (delta-like 1 (Drosophila))|
|DLL1 Antibody||46-984||E, WB||M, R||(IN) DLL1|