Additional NamesNephrin Antibody: NPHN, NPHS1, Renal glomerulus-specific cell adhesion receptor
- Cat. No. 10-401 - Human Kidney Tissue Slide]
Protein Accession NumberNP_004637
DisclaimerThis product is for research use only.
FormulationPhysical State: Liquid
Concentration: 1 mg/mL
Protein GI Number4758822
User NoteOptimal dilutions for each application to be determined by the researcher.
- Kestila M, Lenkkeri U, Mannikko M, et al. Positionally cloned gene for a novel glomerular protein - Nephrin - is mutated in congenital nephrotic syndrome. Mol. Cell 1998; 1:575-582.
- Tryggvason K. Unraveling the mechanisms of glomerular ultrafiltration: nephrin, a key component of the slit diaphragm. J. Am. Soc. Nephrol. 1999; 10:2440-5
- Tryggvason K and Wartiovaara J. Molecular basis of glomerular permselectivity. Curr. Opin. Nephrol. Hypertens. 2001; 10:543-9.]
StorageNephrin antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PurificationNephrin Antibody is affinity chromatography purified via peptide column.
Clonality/CloneThis is a polyclonal Nephrin Antibody.
HostNephrin antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
ImmunogenNephrin antibody was raised against a 16 amino acid synthetic peptide from near the center of human Nephrin.
ApplicationNephrin antibody can be used for detection of Nephrin by immunohistochemistry at 5 μg/mL.
BufferNephrin Antibody is supplied in PBS containing 0.02% sodium azide.
Blocking PeptideCat. No. - 5615P - Nephrin Peptide