LAPTM4B Antibody | catalog# 26-231
Background
LAPTM4B is a multi-pass membrane protein. It belongs to the LAPTM4/LAPTM5 transporter family. LAPTM4b has active role in disease progression of malignant cells and is involved in cell proliferation and multidrug resistance. The genetic polymorphism of LAPTM4B is a potential risk factor for the development of colon cancer and gastric cancer. The research results also indicated that LAPTM4B may be a clinically useful prognostic indicator for ovarian carcinoma and may play a role in human hepatocellular carcinoma.
Description

Western blot analysis of LAPTM4B in 293T cell lysate using LAPTM4B antibody at 1 μg/ml (12% gel).
Specifications
Additional Names
LAPTM4B, LAPTM4beta, LC27Positive Control
- 293T Cell Lysate]
Disclaimer
This product is for research use only.Clonality/Clone
This is a polyclonal antibody.Purification
Antibody is purified by peptide affinity chromatography method.Host
LAPTM4B antibody was raised in rabbit.Please use anti-rabbit secondary antibodies.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LAPTM4B.Application
LAPTM4B antibody can be used for detection of LAPTM4B by ELISA at 1:62500. LAPTM4B antibody can be used for detection of LAPTM4B by western blot at 1 μg/ml, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.Tested Application
E, WBBuffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μl of distilled water. Final antibody concentration is 1 mg/ml.Storage
For short periods of storage (days) store at 4˚C. For longer periods of storage, store LAPTM4B antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.Species Reactivity
HProtein Accession Number
NP_060877Molecular Weight
35 kDaReference
- Cheng, X.J., (2008) Ann. Oncol. 19 (3), 527-532.]

