Immunology Antibodies
Immunology is a tremendously broad research area which focuses on the immune system. Much of the research is centered on the control of the major lymphocytes. B lymphocytes, killer T cells, and helper T cells are the main groups of immune cells. T cells are involved in cell mediated immune response. Helper T cells recognize antigens bound to Class I major histocompatibility complex (Class I MHC) and killer T cells recognize antigens bound to Class II major histocompatibility complex (Class II MHC). B lymphocytes present antigens on unique major histocompatibility complex (MHC) molecules. When this complex on the B lymphocyte is recognized by a matching T cell, the T cell releases cytokines which activate the B lymphocyte and cause it to produce millions of antibodies.
Activation induced cytidine deaminase (AID), interleukin-23 (IL-23), a homolog to toll-like receptor 4 called RP105, interleukin-27 (IL-27), and T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) are all proteins which have strong implications in recent immunology research. Activation induced cytidine deaminase (AID) is necessary for somatic hypermutation and class switch recombination in B lymphocytes. Interleukin-23 (IL-23) has many functions associated with immunology, including enhancement of memory T cell proliferation, enhancement of activated T cell release of IFN-gamma, IL-12, and TNF-α, as well as activating macrophages to produce TNF-α and nitric oxide. Interleukin-27 (IL-27) has a wider influence in immunology by playing a roll in limiting the duration and intensity of responses of the adaptive immune system. T cell immunoglobulin and mucin domain containing protein 1 (TIM1) is genetically linked to asthma, and it is a receptor for hepatitis A virus, and the ligand of TIM1 is T cell immunoglobulin and mucin domain containing protein 4 (TIM4).
ProSci has many immunology antibodies, including antibodies to the proteins mentioned here. ProSci's Immunology antibodies include antibodies against a homolog to toll-like receptor 4 called RP105, activation induced cytidine deaminase (AID), interleukin 23 (IL-23), T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) and interleukin 27 (IL-27). ProSci antibodies are appropriate for ELISA, western blot, and immunohistochemistry (IHC) applications as noted for each immunology antibody.
| Product Name | Catalog # | App. | Reactivity | Description |
|---|---|---|---|---|
| NCAM1 Monoclonal Antibody | 49-121 | WB, IHC, IP, FACS | B, P | Neural Cell Adhesion Molecule |
| NCAM1 Monoclonal Antibody | 49-120 | IHC, FACS | H | Neural Cell Adhesion Molecule |
| NCF4 Antibody | 26-092 | E, WB | H | NCF4 (neutrophil cytosolic factor 4, 40kDa) |
| NCF4 Antibody | 30-133 | E, WB | H | NCF4 (neutrophil cytosolic factor 4, 40kDa) |
| NCR1 Monoclonal Antibody | 49-356 | WB, IHC, FACS | H | Lymphocyte Antigen 94 Homolog |
| NEK6 Antibody | 26-344 | E, WB | H, M, R | NEK6 (NIMA (never in mitosis gene a)-related kinas |
| Nephrosis 1 Antibody | 48-452 | E, IHC | H | Nephrosis 1 |
| NEURL2 Antibody | 30-830 | E, WB | H | NEURL2 (neuralized homolog 2 (Drosophila)) |
| Neuroleukin Antibody | 42-262 | E, WB | H | (IN) GPI / Neuroleukin |
| NF45 Antibody | 46-677 | E, WB, IHC | H | ILF2 / NF45 |
| NFATC4 Antibody | 28-878 | E, WB | H, M, R | NFATC4 (nuclear factor of activated T-cells, cytop |
| NFATC4 Antibody | 27-486 | E, WB | H, M, R, D | NFATC4 (nuclear factor of activated T-cells, cytop |
| NFATC4 Antibody | 27-677 | E, WB, IHC | H, M, R, D | NFATC4 (nuclear factor of activated T-cells, cytop |
| NFE2L1 Antibody | 31-335 | E, WB | H, M, R | NFE2L1 (nuclear factor (erythroid-derived 2)-like |
| NFKBIA Antibody | 31-231 | E, WB | H | NFKBIA (nuclear factor of kappa light polypeptide |
| NFKBIB Antibody | 49-456 | E, WB, IHC, IF, IP | H | Nuclear Factor Of Kappa Light Polypeptide Gene Enh |
| NFRKB Antibody | 25-193 | E, WB | H, M, R | NFRKB (nuclear factor related to kappaB binding pr |
| NFX1 Antibody | 25-227 | E, WB | H | NFX1 (nuclear transcription factor, X-box binding |
| NFX1 Antibody | 27-238 | E, WB | H | NFX1 (nuclear transcription factor, X-box binding |
| NKIRAS1 Antibody | 27-004 | E, WB | H, M, R | NKIRAS1 (NFKB inhibitor interacting Ras-like 1) |
| NKIRAS2 Antibody | 26-858 | E, WB | H, M, R | NKIRAS2 (NFKB inhibitor interacting Ras-like 2) |
| NKIRAS2 Antibody | 30-961 | E, WB | H, M, R | NKIRAS2 (NFKB inhibitor interacting Ras-like 2) |
| NLRP3 Antibody | 42-536 | E, WB | H | (NT) Cryopirin / NALP3 / NLRP3 |
| NMBR Antibody | 27-177 | E, WB | H | NMBR (neuromedin B receptor) |
| NMI Antibody | 28-342 | E, WB | H | NMI (N-myc (and STAT) interactor) |

