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Immunology Antibodies

Immunology is a tremendously broad research area which focuses on the immune system. Much of the research is centered on the control of the major lymphocytes. B lymphocytes, killer T cells, and helper T cells are the main groups of immune cells. T cells are involved in cell mediated immune response. Helper T cells recognize antigens bound to Class I major histocompatibility complex (Class I MHC) and killer T cells recognize antigens bound to Class II major histocompatibility complex (Class II MHC). B lymphocytes present antigens on unique major histocompatibility complex (MHC) molecules. When this complex on the B lymphocyte is recognized by a matching T cell, the T cell releases cytokines which activate the B lymphocyte and cause it to produce millions of antibodies.

Activation induced cytidine deaminase (AID), interleukin-23 (IL-23), a homolog to toll-like receptor 4 called RP105, interleukin-27 (IL-27), and T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) are all proteins which have strong implications in recent immunology research. Activation induced cytidine deaminase (AID) is necessary for somatic hypermutation and class switch recombination in B lymphocytes. Interleukin-23 (IL-23) has many functions associated with immunology, including enhancement of memory T cell proliferation, enhancement of activated T cell release of IFN-gamma, IL-12, and TNF-α, as well as activating macrophages to produce TNF-α and nitric oxide. Interleukin-27 (IL-27) has a wider influence in immunology by playing a roll in limiting the duration and intensity of responses of the adaptive immune system. T cell immunoglobulin and mucin domain containing protein 1 (TIM1) is genetically linked to asthma, and it is a receptor for hepatitis A virus, and the ligand of TIM1 is T cell immunoglobulin and mucin domain containing protein 4 (TIM4).

ProSci has many immunology antibodies, including antibodies to the proteins mentioned here. ProSci's Immunology antibodies include antibodies against a homolog to toll-like receptor 4 called RP105, activation induced cytidine deaminase (AID), interleukin 23 (IL-23), T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) and interleukin 27 (IL-27). ProSci antibodies are appropriate for ELISA, western blot, and immunohistochemistry (IHC) applications as noted for each immunology antibody.

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Product NameCatalog #App.ReactivityDescription
TACI AntibodyXP-5278E, WBHAnti-Human TACI
TACI AntibodyXP-5278BtE, WBHBiotin - Anti-Human TACI
TAP1 Antibody25-880E, WBH, MTAP1 (transporter 1, ATP-binding cassette, sub-fam
Tarc AntibodyXP-5279E, WB, NHAnti-Human TARC
Tarc AntibodyXP-5279BtE, WBHBiotin - Anti-Human TARC
TARS Antibody30-195E, WB, IHCH, M, R, DTARS (threonyl-tRNA synthetase)
TCF12 Antibody5999E, WB, ICCH, M, R(NT) HTF4
TCF12 Antibody31-176E, WBH, M, RTCF12 (transcription factor 12 (HTF4, helix-loop-h
TCIRG1 Antibody6973E, WBH, M, R(NT) T-cell immune regulator 1
TECK AntibodyXP-5725-MEHAnti-TECK, monoclonal
TECK AntibodyXP-5280E, WB, NHAnti-Human TECK
TECK AntibodyXP-5280BtE, WBHBiotin - Anti-Human TECK
TET2 Antibody42-198E, IHCH(IN) TET2
TGFBR3 Antibody46-907EHTGFBR3
THO Complex 5 Antibody49-743E, IHCM, R, XTHO Complex 5
THRAP5 Antibody27-543E, WB, IHCHTHRAP5 (thyroid hormone receptor associated protei
Thymosin AntibodyXG-6168EH, M, R, PAnti-Thymosin
TICAM2 Antibody49-585WB, IHCH(NT) Toll-like Receptor Adaptor Molecule 2
TIM-1 Antibody3811E, WBH, R(IN) T cell immunoglobulin and mucin domain contai
TIM-1 Antibody3809E, WB, IHC, IFH, M(NT) T cell immunoglobulin and mucin domain contai
TIM-4 Antibody3813E, WBH, M, R(CT) T cell immunoglobulin and mucin domain contai
TIM-4 Antibody3815E, WB, ICC, IFH, M(IN) T cell immunoglobulin and mucin domain contai
TL-1A Antibody38-163E, WBHBiotin - Anti-Human TL-1A
TL-1A Antibody38-162E, WBHAnti-Human TL-1A
TLR10 Antibody49-531WB, IHCHToll-like Receptor 10
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