Immunology Antibodies
Immunology is a tremendously broad research area which focuses on the immune system. Much of the research is centered on the control of the major lymphocytes. B lymphocytes, killer T cells, and helper T cells are the main groups of immune cells. T cells are involved in cell mediated immune response. Helper T cells recognize antigens bound to Class I major histocompatibility complex (Class I MHC) and killer T cells recognize antigens bound to Class II major histocompatibility complex (Class II MHC). B lymphocytes present antigens on unique major histocompatibility complex (MHC) molecules. When this complex on the B lymphocyte is recognized by a matching T cell, the T cell releases cytokines which activate the B lymphocyte and cause it to produce millions of antibodies.
Activation induced cytidine deaminase (AID), interleukin-23 (IL-23), a homolog to toll-like receptor 4 called RP105, interleukin-27 (IL-27), and T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) are all proteins which have strong implications in recent immunology research. Activation induced cytidine deaminase (AID) is necessary for somatic hypermutation and class switch recombination in B lymphocytes. Interleukin-23 (IL-23) has many functions associated with immunology, including enhancement of memory T cell proliferation, enhancement of activated T cell release of IFN-gamma, IL-12, and TNF-α, as well as activating macrophages to produce TNF-α and nitric oxide. Interleukin-27 (IL-27) has a wider influence in immunology by playing a roll in limiting the duration and intensity of responses of the adaptive immune system. T cell immunoglobulin and mucin domain containing protein 1 (TIM1) is genetically linked to asthma, and it is a receptor for hepatitis A virus, and the ligand of TIM1 is T cell immunoglobulin and mucin domain containing protein 4 (TIM4).
ProSci has many immunology antibodies, including antibodies to the proteins mentioned here. ProSci's Immunology antibodies include antibodies against a homolog to toll-like receptor 4 called RP105, activation induced cytidine deaminase (AID), interleukin 23 (IL-23), T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) and interleukin 27 (IL-27). ProSci antibodies are appropriate for ELISA, western blot, and immunohistochemistry (IHC) applications as noted for each immunology antibody.
| Product Name | Catalog # | App. | Reactivity | Description |
|---|---|---|---|---|
| TACI Antibody | XP-5278 | E, WB | H | Anti-Human TACI |
| TACI Antibody | XP-5278Bt | E, WB | H | Biotin - Anti-Human TACI |
| TAP1 Antibody | 25-880 | E, WB | H, M | TAP1 (transporter 1, ATP-binding cassette, sub-fam |
| Tarc Antibody | XP-5279 | E, WB, N | H | Anti-Human TARC |
| Tarc Antibody | XP-5279Bt | E, WB | H | Biotin - Anti-Human TARC |
| TARS Antibody | 30-195 | E, WB, IHC | H, M, R, D | TARS (threonyl-tRNA synthetase) |
| TCF12 Antibody | 5999 | E, WB, ICC | H, M, R | (NT) HTF4 |
| TCF12 Antibody | 31-176 | E, WB | H, M, R | TCF12 (transcription factor 12 (HTF4, helix-loop-h |
| TCIRG1 Antibody | 6973 | E, WB | H, M, R | (NT) T-cell immune regulator 1 |
| TECK Antibody | XP-5725-M | E | H | Anti-TECK, monoclonal |
| TECK Antibody | XP-5280 | E, WB, N | H | Anti-Human TECK |
| TECK Antibody | XP-5280Bt | E, WB | H | Biotin - Anti-Human TECK |
| TET2 Antibody | 42-198 | E, IHC | H | (IN) TET2 |
| TGFBR3 Antibody | 46-907 | E | H | TGFBR3 |
| THO Complex 5 Antibody | 49-743 | E, IHC | M, R, X | THO Complex 5 |
| THRAP5 Antibody | 27-543 | E, WB, IHC | H | THRAP5 (thyroid hormone receptor associated protei |
| Thymosin Antibody | XG-6168 | E | H, M, R, P | Anti-Thymosin |
| TICAM2 Antibody | 49-585 | WB, IHC | H | (NT) Toll-like Receptor Adaptor Molecule 2 |
| TIM-1 Antibody | 3811 | E, WB | H, R | (IN) T cell immunoglobulin and mucin domain contai |
| TIM-1 Antibody | 3809 | E, WB, IHC, IF | H, M | (NT) T cell immunoglobulin and mucin domain contai |
| TIM-4 Antibody | 3813 | E, WB | H, M, R | (CT) T cell immunoglobulin and mucin domain contai |
| TIM-4 Antibody | 3815 | E, WB, ICC, IF | H, M | (IN) T cell immunoglobulin and mucin domain contai |
| TL-1A Antibody | 38-163 | E, WB | H | Biotin - Anti-Human TL-1A |
| TL-1A Antibody | 38-162 | E, WB | H | Anti-Human TL-1A |
| TLR10 Antibody | 49-531 | WB, IHC | H | Toll-like Receptor 10 |

