Immunology Antibodies
Immunology is a tremendously broad research area which focuses on the immune system. Much of the research is centered on the control of the major lymphocytes. B lymphocytes, killer T cells, and helper T cells are the main groups of immune cells. T cells are involved in cell mediated immune response. Helper T cells recognize antigens bound to Class I major histocompatibility complex (Class I MHC) and killer T cells recognize antigens bound to Class II major histocompatibility complex (Class II MHC). B lymphocytes present antigens on unique major histocompatibility complex (MHC) molecules. When this complex on the B lymphocyte is recognized by a matching T cell, the T cell releases cytokines which activate the B lymphocyte and cause it to produce millions of antibodies.
Activation induced cytidine deaminase (AID), interleukin-23 (IL-23), a homolog to toll-like receptor 4 called RP105, interleukin-27 (IL-27), and T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) are all proteins which have strong implications in recent immunology research. Activation induced cytidine deaminase (AID) is necessary for somatic hypermutation and class switch recombination in B lymphocytes. Interleukin-23 (IL-23) has many functions associated with immunology, including enhancement of memory T cell proliferation, enhancement of activated T cell release of IFN-gamma, IL-12, and TNF-α, as well as activating macrophages to produce TNF-α and nitric oxide. Interleukin-27 (IL-27) has a wider influence in immunology by playing a roll in limiting the duration and intensity of responses of the adaptive immune system. T cell immunoglobulin and mucin domain containing protein 1 (TIM1) is genetically linked to asthma, and it is a receptor for hepatitis A virus, and the ligand of TIM1 is T cell immunoglobulin and mucin domain containing protein 4 (TIM4).
ProSci has many immunology antibodies, including antibodies to the proteins mentioned here. ProSci's Immunology antibodies include antibodies against a homolog to toll-like receptor 4 called RP105, activation induced cytidine deaminase (AID), interleukin 23 (IL-23), T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) and interleukin 27 (IL-27). ProSci antibodies are appropriate for ELISA, western blot, and immunohistochemistry (IHC) applications as noted for each immunology antibody.
| Product Name | Catalog # | App. | Reactivity | Description |
|---|---|---|---|---|
| S1P1 Antibody | 4809 | E, WB, IHC | H, M, R | (CT) Sphingosine-1-phosphate receptor 1 |
| SAC Antibody | 26-233 | E, WB | H, M, R | SAC (adenylate cyclase type 10 isoform 1) |
| SAMHD1 Antibody | 26-987 | E, WB | H, M | SAMHD1 (SAM domain and HD domain 1) |
| SAMSN Antibody | 7079 | E, WB | H | (CT) SAM domain SH3 domain and nuclear localizatio |
| SARM1 Monoclonal Antibody | 49-353 | IHC, IP | H | Sterile Alpha And TIR Motif Containing 1 |
| SCF Antibody | XP-5264 | E, WB | H | Anti-Human SCF - Rabbit |
| SCF Antibody | XP-5265 | E, WB | H | Anti-Human SCF - Goat |
| SCF Antibody | XP-5266 | E, WB, N | M | Anti-Murine Stem Cell Factor |
| SCF Antibody | XP-5267 | E, WB, N | R | Anti-Rat SCF |
| SCF Antibody | XP-5723-M | E | H | Anti-SCF, monoclonal |
| SCF Antibody | XP-5264Bt | E, WB | H | Biotin - Anti-Human SCF - Rabbit |
| SCF Antibody | XP-5265Bt | E, WB | H | Biotin - Anti-Human SCF - Goat |
| SCF Antibody | XP-5266Bt | E, WB | M | Biotin - Anti-Murine SCF |
| SCF Antibody | XP-5267Bt | E, WB | R | Biotin - Anti-Rat SCF |
| SCGB3A1 Antibody | 42-085 | E | H | (IN) SCGB3A1 / UGRP2 |
| SCOTIN Antibody | 26-202 | E, WB | H | SCOTIN (protein shisa-5 precursor) |
| SCYE1 Antibody | 29-340 | E, WB | H, D | SCYE1 (small inducible cytokine subfamily E, membe |
| SDCBP2 Antibody | 26-996 | E, WB | H | SDCBP2 (syndecan binding protein (syntenin) 2) |
| SELPLG Monoclonal Antibody | 51-120 | IHC, FACS | n/a | (CT) (CT) Selectin P Ligand |
| SELS Antibody | 26-281 | E, WB | H | SELS (selenoprotein S) |
| Septin 6 Antibody | 30-177 | E, WB | H, M | SEPT6 (septin 6) |
| SERPINA1 Antibody | XW-7000 | E, WB | H | a-1 antitrypsin |
| SERPINA1 Antibody | 30-998 | E, WB, IHC | H | SERPINA1 (serpin peptidase inhibitor, clade A, mem |
| SET Antibody | 49-309 | WB, IHC | H | SET Translocation |
| SH3BP2 Antibody | 27-092 | E, WB | H, M, R | SH3BP2 (SH3-domain binding protein 2) |

