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Immunology Antibodies

Immunology is a tremendously broad research area which focuses on the immune system. Much of the research is centered on the control of the major lymphocytes. B lymphocytes, killer T cells, and helper T cells are the main groups of immune cells. T cells are involved in cell mediated immune response. Helper T cells recognize antigens bound to Class I major histocompatibility complex (Class I MHC) and killer T cells recognize antigens bound to Class II major histocompatibility complex (Class II MHC). B lymphocytes present antigens on unique major histocompatibility complex (MHC) molecules. When this complex on the B lymphocyte is recognized by a matching T cell, the T cell releases cytokines which activate the B lymphocyte and cause it to produce millions of antibodies.

Activation induced cytidine deaminase (AID), interleukin-23 (IL-23), a homolog to toll-like receptor 4 called RP105, interleukin-27 (IL-27), and T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) are all proteins which have strong implications in recent immunology research. Activation induced cytidine deaminase (AID) is necessary for somatic hypermutation and class switch recombination in B lymphocytes. Interleukin-23 (IL-23) has many functions associated with immunology, including enhancement of memory T cell proliferation, enhancement of activated T cell release of IFN-gamma, IL-12, and TNF-α, as well as activating macrophages to produce TNF-α and nitric oxide. Interleukin-27 (IL-27) has a wider influence in immunology by playing a roll in limiting the duration and intensity of responses of the adaptive immune system. T cell immunoglobulin and mucin domain containing protein 1 (TIM1) is genetically linked to asthma, and it is a receptor for hepatitis A virus, and the ligand of TIM1 is T cell immunoglobulin and mucin domain containing protein 4 (TIM4).

ProSci has many immunology antibodies, including antibodies to the proteins mentioned here. ProSci's Immunology antibodies include antibodies against a homolog to toll-like receptor 4 called RP105, activation induced cytidine deaminase (AID), interleukin 23 (IL-23), T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) and interleukin 27 (IL-27). ProSci antibodies are appropriate for ELISA, western blot, and immunohistochemistry (IHC) applications as noted for each immunology antibody.

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Product NameCatalog #App.ReactivityDescription
S1P1 Antibody4809E, WB, IHCH, M, R(CT) Sphingosine-1-phosphate receptor 1
SAC Antibody26-233E, WBH, M, RSAC (adenylate cyclase type 10 isoform 1)
SAMHD1 Antibody26-987E, WBH, MSAMHD1 (SAM domain and HD domain 1)
SAMSN Antibody7079E, WBH(CT) SAM domain SH3 domain and nuclear localizatio
SARM1 Monoclonal Antibody49-353IHC, IPHSterile Alpha And TIR Motif Containing 1
SCF AntibodyXP-5264E, WBHAnti-Human SCF - Rabbit
SCF AntibodyXP-5265E, WBHAnti-Human SCF - Goat
SCF AntibodyXP-5266E, WB, NMAnti-Murine Stem Cell Factor
SCF AntibodyXP-5267E, WB, NRAnti-Rat SCF
SCF AntibodyXP-5723-MEHAnti-SCF, monoclonal
SCF AntibodyXP-5264BtE, WBHBiotin - Anti-Human SCF - Rabbit
SCF AntibodyXP-5265BtE, WBHBiotin - Anti-Human SCF - Goat
SCF AntibodyXP-5266BtE, WBMBiotin - Anti-Murine SCF
SCF AntibodyXP-5267BtE, WBRBiotin - Anti-Rat SCF
SCGB3A1 Antibody42-085EH(IN) SCGB3A1 / UGRP2
SCOTIN Antibody26-202E, WBHSCOTIN (protein shisa-5 precursor)
SCYE1 Antibody29-340E, WBH, DSCYE1 (small inducible cytokine subfamily E, membe
SDCBP2 Antibody26-996E, WBHSDCBP2 (syndecan binding protein (syntenin) 2)
SELPLG Monoclonal Antibody51-120IHC, FACSn/a(CT) (CT) Selectin P Ligand
SELS Antibody26-281E, WBHSELS (selenoprotein S)
Septin 6 Antibody30-177E, WBH, MSEPT6 (septin 6)
SERPINA1 AntibodyXW-7000E, WBHa-1 antitrypsin
SERPINA1 Antibody30-998E, WB, IHCHSERPINA1 (serpin peptidase inhibitor, clade A, mem
SET Antibody49-309WB, IHCHSET Translocation
SH3BP2 Antibody27-092E, WBH, M, RSH3BP2 (SH3-domain binding protein 2)
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