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Immunology Antibodies

Immunology is a tremendously broad research area which focuses on the immune system. Much of the research is centered on the control of the major lymphocytes. B lymphocytes, killer T cells, and helper T cells are the main groups of immune cells. T cells are involved in cell mediated immune response. Helper T cells recognize antigens bound to Class I major histocompatibility complex (Class I MHC) and killer T cells recognize antigens bound to Class II major histocompatibility complex (Class II MHC). B lymphocytes present antigens on unique major histocompatibility complex (MHC) molecules. When this complex on the B lymphocyte is recognized by a matching T cell, the T cell releases cytokines which activate the B lymphocyte and cause it to produce millions of antibodies.

Activation induced cytidine deaminase (AID), interleukin-23 (IL-23), a homolog to toll-like receptor 4 called RP105, interleukin-27 (IL-27), and T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) are all proteins which have strong implications in recent immunology research. Activation induced cytidine deaminase (AID) is necessary for somatic hypermutation and class switch recombination in B lymphocytes. Interleukin-23 (IL-23) has many functions associated with immunology, including enhancement of memory T cell proliferation, enhancement of activated T cell release of IFN-gamma, IL-12, and TNF-α, as well as activating macrophages to produce TNF-α and nitric oxide. Interleukin-27 (IL-27) has a wider influence in immunology by playing a roll in limiting the duration and intensity of responses of the adaptive immune system. T cell immunoglobulin and mucin domain containing protein 1 (TIM1) is genetically linked to asthma, and it is a receptor for hepatitis A virus, and the ligand of TIM1 is T cell immunoglobulin and mucin domain containing protein 4 (TIM4).

ProSci has many immunology antibodies, including antibodies to the proteins mentioned here. ProSci's Immunology antibodies include antibodies against a homolog to toll-like receptor 4 called RP105, activation induced cytidine deaminase (AID), interleukin 23 (IL-23), T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) and interleukin 27 (IL-27). ProSci antibodies are appropriate for ELISA, western blot, and immunohistochemistry (IHC) applications as noted for each immunology antibody.

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Product NameCatalog #App.ReactivityDescription
RAB11B Antibody30-384E, WBH, M, RRAB11B (RAB11B, member RAS oncogene family)
RAB38 Antibody25-787E, WBH, M, RRAB38 (RAB38, member RAS oncogene family)
RAB3A Antibody31-123E, WBHRAB3A (RAB3A, member RAS oncogene family)
RAB3D Antibody31-124E, WBHRAB3D (RAB3D, member RAS oncogene family)
RAB40A Antibody30-832E, WBHRAB40A (RAB40A, member RAS oncogene family)
RAB40B Antibody26-639E, WBH, M, RRAB40B (RAB40B, member RAS oncogene family)
RAB8A Antibody27-233E, WBH, DRAB8A (RAB8A, member RAS oncogene family)
RACGAP1 Antibody27-437E, WBH, DRACGAP1 (Rac GTPase activating protein 1)
Ramp1 Antibody46-890E, WBRRamp1 (C-Term., mouse)
RASGEF1A Antibody27-032E, WBHRASGEF1A (RasGEF domain family, member 1A)
RASGEF1C Antibody27-069E, WBH, M, RRASGEF1C (RasGEF domain family, member 1C)
RASL10A Antibody26-637E, WBHRASL10A (RAS-like, family 10, member A)
RBM14 Antibody29-369E, WBH, M, RRBM14 (RNA binding motif protein 14)
RC3H1 Antibody7251E, WBH, M, R(CT) Ring finger and CCCH-type domains 1
RCAN1 Antibody25-434E, WBH, M, RRCAN1 (regulator of calcineurin 1)
RCAN3 Antibody25-642E, WBHRCAN3 (RCAN family member 3)
REL Antibody27-241E, WBHREL (v-rel reticuloendotheliosis viral oncogene ho
RELA Antibody31-180E, WBHRELA (v-rel reticuloendotheliosis viral oncogene h
RFP2 Antibody28-015E, WBH, M, R, DRFP2 (tripartite motif-containing protein 13 isofo
RFX1 Antibody25-416E, WBH, M, RRFX1 (regulatory factor X, 1 (influences HLA class
RGS3 Antibody31-064E, WBH, M, RRGS3 (regulator of G-protein signaling 3)
RGS6 Antibody27-989E, WB, IHCH, M, R, DRGS6 (regulator of G-protein signalling 6)
RGS6 Antibody25-179E, WBH, RRGS6 (regulator of G-protein signaling 6)
RGS9 Antibody31-075E, WB, IHCH, M, R, DRGS9 (regulator of G-protein signalling 9)
RHOC Antibody27-070E, WBH, M, R, D, Ce, DsRHOC (ras homolog gene family, member C)
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