Immunology Antibodies
Immunology is a tremendously broad research area which focuses on the immune system. Much of the research is centered on the control of the major lymphocytes. B lymphocytes, killer T cells, and helper T cells are the main groups of immune cells. T cells are involved in cell mediated immune response. Helper T cells recognize antigens bound to Class I major histocompatibility complex (Class I MHC) and killer T cells recognize antigens bound to Class II major histocompatibility complex (Class II MHC). B lymphocytes present antigens on unique major histocompatibility complex (MHC) molecules. When this complex on the B lymphocyte is recognized by a matching T cell, the T cell releases cytokines which activate the B lymphocyte and cause it to produce millions of antibodies.
Activation induced cytidine deaminase (AID), interleukin-23 (IL-23), a homolog to toll-like receptor 4 called RP105, interleukin-27 (IL-27), and T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) are all proteins which have strong implications in recent immunology research. Activation induced cytidine deaminase (AID) is necessary for somatic hypermutation and class switch recombination in B lymphocytes. Interleukin-23 (IL-23) has many functions associated with immunology, including enhancement of memory T cell proliferation, enhancement of activated T cell release of IFN-gamma, IL-12, and TNF-α, as well as activating macrophages to produce TNF-α and nitric oxide. Interleukin-27 (IL-27) has a wider influence in immunology by playing a roll in limiting the duration and intensity of responses of the adaptive immune system. T cell immunoglobulin and mucin domain containing protein 1 (TIM1) is genetically linked to asthma, and it is a receptor for hepatitis A virus, and the ligand of TIM1 is T cell immunoglobulin and mucin domain containing protein 4 (TIM4).
ProSci has many immunology antibodies, including antibodies to the proteins mentioned here. ProSci's Immunology antibodies include antibodies against a homolog to toll-like receptor 4 called RP105, activation induced cytidine deaminase (AID), interleukin 23 (IL-23), T cell immunoglobulin and mucin domain containing protein 1 and 4 (TIM1 and TIM4) and interleukin 27 (IL-27). ProSci antibodies are appropriate for ELISA, western blot, and immunohistochemistry (IHC) applications as noted for each immunology antibody.
| Product Name | Catalog # | App. | Reactivity | Description |
|---|---|---|---|---|
| RAB11B Antibody | 30-384 | E, WB | H, M, R | RAB11B (RAB11B, member RAS oncogene family) |
| RAB38 Antibody | 25-787 | E, WB | H, M, R | RAB38 (RAB38, member RAS oncogene family) |
| RAB3A Antibody | 31-123 | E, WB | H | RAB3A (RAB3A, member RAS oncogene family) |
| RAB3D Antibody | 31-124 | E, WB | H | RAB3D (RAB3D, member RAS oncogene family) |
| RAB40A Antibody | 30-832 | E, WB | H | RAB40A (RAB40A, member RAS oncogene family) |
| RAB40B Antibody | 26-639 | E, WB | H, M, R | RAB40B (RAB40B, member RAS oncogene family) |
| RAB8A Antibody | 27-233 | E, WB | H, D | RAB8A (RAB8A, member RAS oncogene family) |
| RACGAP1 Antibody | 27-437 | E, WB | H, D | RACGAP1 (Rac GTPase activating protein 1) |
| Ramp1 Antibody | 46-890 | E, WB | R | Ramp1 (C-Term., mouse) |
| RASGEF1A Antibody | 27-032 | E, WB | H | RASGEF1A (RasGEF domain family, member 1A) |
| RASGEF1C Antibody | 27-069 | E, WB | H, M, R | RASGEF1C (RasGEF domain family, member 1C) |
| RASL10A Antibody | 26-637 | E, WB | H | RASL10A (RAS-like, family 10, member A) |
| RBM14 Antibody | 29-369 | E, WB | H, M, R | RBM14 (RNA binding motif protein 14) |
| RC3H1 Antibody | 7251 | E, WB | H, M, R | (CT) Ring finger and CCCH-type domains 1 |
| RCAN1 Antibody | 25-434 | E, WB | H, M, R | RCAN1 (regulator of calcineurin 1) |
| RCAN3 Antibody | 25-642 | E, WB | H | RCAN3 (RCAN family member 3) |
| REL Antibody | 27-241 | E, WB | H | REL (v-rel reticuloendotheliosis viral oncogene ho |
| RELA Antibody | 31-180 | E, WB | H | RELA (v-rel reticuloendotheliosis viral oncogene h |
| RFP2 Antibody | 28-015 | E, WB | H, M, R, D | RFP2 (tripartite motif-containing protein 13 isofo |
| RFX1 Antibody | 25-416 | E, WB | H, M, R | RFX1 (regulatory factor X, 1 (influences HLA class |
| RGS3 Antibody | 31-064 | E, WB | H, M, R | RGS3 (regulator of G-protein signaling 3) |
| RGS6 Antibody | 27-989 | E, WB, IHC | H, M, R, D | RGS6 (regulator of G-protein signalling 6) |
| RGS6 Antibody | 25-179 | E, WB | H, R | RGS6 (regulator of G-protein signaling 6) |
| RGS9 Antibody | 31-075 | E, WB, IHC | H, M, R, D | RGS9 (regulator of G-protein signalling 9) |
| RHOC Antibody | 27-070 | E, WB | H, M, R, D, Ce, Ds | RHOC (ras homolog gene family, member C) |

